1st Edition
Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications
Dietary supplements and nutraceuticals such as Vitamin A and D, Omega-3 and probiotics are used as part of the cancer treatment as complimenting the main therapy. Several Nutraceuticals have shown to boost the immune responses, while emerging clinical studies and other research suggests that some plant-based agents may, indeed, impact late-stage cancer, influencing molecular processes corrupted by tumor cells to evade detection, expand clonally, and invade surrounding tissues.
Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications
is an attempt to collect evidence and related clinical information of application of Nutraceuticals to be used in cancer treatment or compliment the cancer treatment. It contains 16 chapters written by experts in related field’s and covers many different aspects of the formulation and development of Nutraceuticals for cancer applications. This book covers efficacy, safety and toxicological aspects of nutraceuticals. It also addresses various novel drug delivery systems of nutraceuticals with anticancer properties, as well as nutraceuticals as supplements for cancer prevention.
Features:
- Offers a comprehensive view of neutraceuticals’ role in cancer prevention and treatment
- Covers the applications and implications of neutraceuticals in prostate, colorectal, breast and gynecological cancers
- Discusses the principles of neutrigenomics and neutrigenetics in cancer prevention
- Explors the role of probiotics and micronutrients in cancer treatment and prevention
Nutraceuticals can alter the gut microbiota. Gut microbiome undergoes changes during the disease status and followed by the cancer treatment. Nutraceutical’s role in proliferation and prevention of gynecological cancers, nutraceutical’s role in proliferation and prevention of prostate cancer and role of micronutrients in cancer prevention, both pros and cons, are some of the topics discussed in various chapters in this book. This book is addressed to scientists, clinicians, and students who are working in the area of Nutraceutical applications in cancer treatment.
Contents
Preface......................................................................................................................vii
Editors .......................................................................................................................ix
Contributors ..............................................................................................................xi
Chapter 1 Role of Micronutrients in Cancer Prevention and
Intervention—Pros and Cons ...............................................................1
Anjelika Chatwal and Yashwant V. Pathak
Chapter 2 Nutraceuticals as Supplements for Cancer Prevention ....................... 19
Nicholas Micciche, Brianna Choyce, and Yashwant V. Pathak
Chapter 3 Nutraceutical’s Role in Proliferation and Prevention
of Prostate Cancer .............................................................................. 39
Raghunandan Yendapally and Donald Sikazwe
Chapter 4 Nutraceutical’s Role in Proliferation and Prevention
of Colorectal Cancer .......................................................................... 61
Mayur M. Patel, Shruti U. Rawal, and Jayvadan K. Patel
Chapter 5 Nutraceuticals’ Role in Proliferation and Prevention
of Breast Cancer ............................................................................... 115
Sadaf Aslam and Beata Casanas
Chapter 6 Nutraceutical’s Role in Proliferation and Prevention
of Gynecological Cancers ................................................................ 133
Aaishwarya B. Deshmukh, Jayvadan K. Patel, and Bharat Mishra
Chapter 7 Mechanism and Role of Probiotics in Suppressing
Bowel Cancer ..............................................................................153
Aaishwarya B. Deshmukh, Jayvadan K. Patel, and Bharat Mishra
Chapter 8 Effect of Nutraceuticals on Gut Microbiota—What Is the
Deal in Cancer? ................................................................................ 171
Andréa Burgess, Asra Sami, and Sheeba Varghese Gupta
Chapter 9 Nutrigenomics and Nutrigenetics in Cancer Prevention .................. 191
Komal Parmar and Jayvadan K. Patel
Chapter 10 Novel Drug Delivery Systems for Nutraceuticals with
Anticancer Properties .......................................................................207
Priyanka Bhatt, Imran Vhora, and Rohan Lalani
Chapter 11 Delivery Strategies and Formulation Approaches of
Anticancer Nutraceuticals ................................................................ 239
Sunita Dahiya and Rajiv Dahiya
Chapter 12 Efficacy, Safety, and Toxicological Aspects of Nutraceuticals ........269
Jayvadan K. Patel and Anita Patel
Chapter 13 Dietary Habits and Susceptibility to Various Cancers ..................... 291
Kimberly Padawer and Yashwant V. Pathak
Chapter 14 Indian Diet and Cancer Prevention ..................................................307
Vasudha Pritipaul, Asra Sami, and Sheeba Varghese Gupta
Chapter 15 Dietary Isoflavones-Mechanism and Efficacy in Cancer
Prevention and Treatment ................................................................. 325
Richa Dayaramani and Jayvadan K. Patel
Index ...................................................................................................................... 341
Biography
Sheeba Varghese Gupta, MPharm, PhD, is an associate professor, Department
of Pharmaceutical Sciences, College of Pharmacy, University of South Florida,
Tampa, Florida. She received her PhD at Wayne State University, Michigan, and
earned her MS in Pharmaceutical Chemistry from Bharati Vidhya Peeth Poona
College of Pharmacy, University of Pune, Maharashtra, India. Her research interests
are novel drug delivery systems, improving oral absorption of poorly absorbed
drugs, and patient outcomes. She has authored many peer-reviewed publications,
book chapters and abstracts.
Dr. Yashwant V. Pathak completed his PhD in Pharmaceutical Technology at
Nagpur University, India, and EMBA and MS in Conflict Management at Sullivan
University. He is professor and associate dean for Faculty Affairs at Taneja College
of Pharmacy, University of South Florida. Tampa, Florida. With extensive experience
in academia as well as industry, he has more than 200 research publications,
including research papers; chapters and reviews; 2 patent and 2 patent application;
and 28 edited books published, including 12 books in nanotechnology and 10 in
nutraceuticals and drug delivery systems. He has several books in cultural studies
and conflict management. He has received several national and international awards.
Dr. Pathak was a recipient of Fulbright Senior Scholar award for Indonesia in the
year 2016–2017. Dr. Yashwant V. Pathak is also an adjunct professor at Faculty of
Pharmacy, Airlangga University, Surabaya, Indonesia.
'This book attempts to summarize the existing evidence regarding mechanisms of action and applications of a broad range of nutraceuticals either for
chemoprophylaxis of solid tumors or as supplements to alleviate chemotherapy-induced toxicities. In addition, two chapters discuss delivery systems utilized for administration of nutraceuticals. One chapter is dedicated to discussion, although rather limited, of the Indian diet and its role in cancer prevention; this is a valuable and unique feature since India has the lowest incidence of cancers in comparison to the Americas, Africa, and China.
'The purpose [of this book] is to summarize the data on the role of nutraceuticals in cancer management. This is a highly noteworthy and ambitious goal. The results of multiple surveys, personal encounters, and experiences shared by healthcare practitioners reflect a tremendous public interest on the subject as well as consumption of the supplements in discussion. It is difficult to underestimate the usefulness of such a book for medical and allied health educational purposes.'
-- Anna Dushenkov, Fairleigh Dickinson University
