Adrenal Toxicology

1st Edition

Philip W. Harvey, David J. Everett, Christopher J. Springall

CRC Press
Published October 22, 2008
Reference - 352 Pages - 36 Color & 16 B/W Illustrations
ISBN 9781420061291 - CAT# 61291
Series: Target Organ Toxicology Series

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Summary

Despite being regarded as the most common toxicological target in the endocrine system, the adrenal gland has often been neglected in regulatory testing. Adrenal Toxicology addresses the increased interest in adrenocortical toxicology and the need for a resource that makes techniques available to examine adrenal endocrine disruption.

Examining current techniques and the latest advancements, Adrenal Toxicology reviews the endocrinology, pharmacology, pathology and toxicology of the adrenal gland. This text provides information on the range of drugs and chemicals that affect adrenocortical function and suggests standardized approaches for in vivo and in vitro assessment. This volume also presents recent developments in the molecular mechanisms of toxicity to the adrenal cortex and medulla, and considers environmental adrenal endocrine disruption in sentinel species.

Adrenal Toxicology:

  • reflects the major developments made over the past decade
  • focuses on the latest research techniques, including their uses and limitations
  • provides an integrated strategy for adrenal toxicology evaluation
  • identifies knowledge and data gaps, providing impetus for regulatory consideration

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