With detailed contributions from 45 renowned international authorities, this Third Edition stands alone as the most comprehensive, contemporary view of the biology, physiology, and management of acute coronary syndromes (ACS)-offering 32 chapters that span the state-of-the science in the field and provide intriguing discussions on CRP and other disease markers, microcirculation, stem cell therapy, and the development of specialized centers for ACS treatment.
Table of Contents
Inflammation in ACS. Genetic Basis of Acute Coronary Syndromes. Plaque Rupture: Pathological and Anatomical Considerations. Embolization as a Pathological Mechanism. Plaque Vulnerability: (Insights from Intravascular Ultrasound, Optical Coherence Tomography, Thermography). Differences Between Unstable Angina and Acute Myocardial Infarction: The Pathophysiological and Clinical Spectrum. Acute ST-Segment Elevation Myocardial Infarction: The Open Artery and Tissue Reperfusion. Prehospital Treatment of Acute Myocardial Infarction. Thrombolysis for Acute Myocardial Infarction: First-and Second-Generation Agents. Third-Generation Thrombolytic Agents (Reteplase, Tenectaplase, Lanetoplase) and Combined Fibrinoplatelet Lysis for Acute Myocardial Infarction. Diagnosis of Acute Coronary Syndromes in the Emergency Department: Evolution of Chest Pain Centers. Facilitated PCI for MI. Specialized Centers for ACS/MI. The Role of Troponin in Risk Stratification. BNP and ProBNP. Role of CRP, Myeloperoxidase, N-tyrosine and Other Markers. Early Invasive vs. Conservative Strategies for ACS Management. Intravenous Glycoprotein IIb/IIIa Receptor Inhibitor Agents for Acute Coronary Syndromes. Role of P2Y12 Blockade (Clopidogrel) in ACS. Dosing and Aspirin. Antithrombin Therapy (Unfractionated Heparin, Bivalirudin, Low Molecular Weight Heparin) in Acute Coronary Syndromes. Bedside Anticoagulant Testing. Bedside Platelet Monitoring. Statins and Plaque Stabilization. Diabetes in ACS. Myocardial Rupture: Pathobiology, Diagnosis, Medical Management, and Surgical Intervention. The Microcirculation in MI. Stem Cells for ACS. Cardiogenic Shock and Advanced Killip Class. Treatment of Acute Myocardial Infarction: International and Regional Differences. Quality of Care in ACS/MI. Cost Effectiveness of New Diagnostic Tools and Therapies for ACS.
"…This well written third edition maintains its place as one of the definitive references on the subject of acute coronary syndromes."
"….well done and heavily referenced."
-The American Journal of Cardiology
"…a thorough volume with an impressive group of contributors…recommended for all medical libraries."