1st Edition

The Aorta Structure, Function, Dysfunction and Diseases

    374 Pages 300 B/W Illustrations
    by CRC Press

    This guide thoroughly discusses all aspects of the aorta, including embryology, anatomy, health, and disease. This highly focused text concentrates on the functions of the aorta, not simply as a pathophysiological entity, but also as a significant prognostic indicator for cardiovascular events.

    An essential tool for practicing cardiologists and trainees, this guide:

    • covers all aortic diseases, including aortic aneurysms, aortic dissections, intramular hematoma, congenital heart diseases, heritable connective tissue disorders, and aortic trauma
    • discusses the aging aorta, aorta and pregnancy, and chest pain of aortic origin
    • examines data related to molecular/genetic mechanisms in aortic function and diseases
    • presents established and cutting-edge techniques for the evaluationof aortic function and structure

    Historical perspectives: the aorta in time

    Charles F Wooley and Mark E Silverman

    The aorta: embryology, anatomy, and pathology

    Siew Yen Ho and Mary N Sheppard

    Basic concepts and regulation of aortic function

    Junichiro Hashimoto and Michael F O’Rourke

    Aorta–aortic valve interrelationships

    Charles F Wooley, Elizabeth A Sparks, and Harisios Boudoulas

    Aorta–peripheral arteries interrelationships

    Junichiro Hashimoto and Michael F O’Rourke

    Aortic function: methods of evaluation

    Charalambos Vlachopoulos, Konstantinos Aznaouridis, Christodoulos Stefanadis, and Harisios Boudoulas

    Aortic function in pregnancy

    Charalambos Vlachopoulos, Manolis Vavouranakis, Harisios Boudoulas, and Christodoulos Stefanadis

    Aging and aortic function

    Charalambos Vlachopoulos, Nikolaos Alexopoulos, Harisios Boudoulas, and Christodoulos Stefanadis

    Aortic and carotid function as a predictor of cardiovascular outcomes

    Michael E Safar and Jacques Blacher

    Aortic pain

    Charles F Wooley, Eliazbeth A Sparks, and Harisios Boudoulas

    Aortic function in coronary artery disease

    Charalambos Vlachopoulos, Nikolaos Alexopoulos, Harisios Boudoulas, and Christodoulos Stefanadis

    Aortic function in end-stage renal disease, diabetes mellitus, and arterial hypertension

    John Lekakis

    Aortic function in congenital heart disease

    Stella Brili, Michael Gatzoulis, Christodoulos Stefanadis, and Harisios Boudoulas

    Aortic function in beta-thalassemia major

    Dimitrios A Stakos, Dimitrios Margaritis, Dimitrios N Tziakas, and Harisios Boudoulas

    Heritable connective tissue disorders: the molecular basis for aortopathy. The Marfan syndrome,

    annuloaortic ectasia, Ehlers-Danlos syndrome, polycystic kidney disease, and miscellaneous

    Elizabeth A Sparks, Harisios Boudoulas, and Charles F Wooley

    Inflammation and aortic function

    Charalambos Vlachopoulos, Panagiota Pietri, and Christodoulos Stefanadis

    Inflammation and aortic valve disease

    Konstantinos Toutouzas, Eleftherios Tsiamis, Elli Stefanadi, Harisios Boudoulas, Magdi Yacoub, and

    Christodoulos Stefanadis

    Atherosclerosis: aortic wall thickness and atherosclerotic plaques

    Constantina Aggeli, Konstantinos Toutouzas, Harisios Boudoulas and Christodoulos Stefanadis

    Aortic function: modification with non-pharmacologic means

    Charalambos Vlachopoulos, Nikolaos Alexopoulos, and Christodoulos Stefanadis

    Aortic function: modification with pharmacologic agents

    Filippos Triposkiadis

    Echocardiography

    Petros Nihoyannopoulos

    Magnetic resonance imaging and computed tomography

    Subha V Raman and Vincent E Brinkman

    Catheter angiography

    Achilles Chatziioannou and Lambros Vlachos

    Intramural hematoma and atherosclerotic ulcer

    Ana García-Lopez and José L Zamorano

    Triggers of aortic dissection

    Marina Feldman and John A Elefteriades

    Thoracic aortic aneurysm: pathophysiology, clinical presentation, diagnostic evaluation, and

    management

    Chris K Rokkas and Constantine E Anagnostopoulos

    Abdominal aortic aneurysm: pathophysiology, clinical presentation, diagnostic evaluation, and

    management

    Christos D Liapis and John D Kakisis

    Endovascular therapy of aortic diseases

    Chris Klonaris, Athanasios Katsargyris, and Elias Bastounis

    Trauma of the thoracic aorta

    John D Symbas and Panagiotis N Symbas

    Concluding remarks and future directions

    Harisios Boudoulas and Christodoulos Stefanadis

    Index

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    Historical perspectives: the aorta in time. The aorta: embryology, anatomy, and pathology. Basic concepts and regulation of aortic function. Aorta–aortic valve interrelationships. Aorta–peripheral arteries interrelationships. Aortic function: methods of evaluation. Aortic function in pregnancy. Aging and aortic function. Aortic and carotid function as a predictor of cardiovascular outcomes. Aortic pain. Aortic function in coronary artery disease. Aortic function in end-stage renal disease, diabetes mellitus, and arterial hypertension. Aortic function in congenital heart disease. Aortic function in beta-thalassemia major. Heritable connective tissue disorders: the molecular basis for aortopathy. The Marfan syndrome, annuloaortic ectasia, Ehlers-Danlos syndrome, polycystic kidney disease, and miscellaneous. Inflammation and aortic function. Inflammation and aortic valve disease. Atherosclerosis: aortic wall thickness and atherosclerotic plaques. Aortic function: modification with non-pharmacologic means. Aortic function: modification with pharmacologic agents. Echocardiography. Magnetic resonance imaging and computed tomography. Catheter angiography. Intramural hematoma and atherosclerotic ulcer. Triggers of aortic dissection. Thoracic aortic aneurysm: pathophysiology, clinical presentation, diagnostic evaluation, and. management. Abdominal aortic aneurysm: pathophysiology, clinical presentation, diagnostic evaluation, and. management. Endovascular therapy of aortic diseases. Trauma of the thoracic aorta. Concluding remarks and future directions. Index.

    Biography

    HARISIOS BOUDOULAS is Professor of Medicine/Cardiology (emeritus), The Ohio State University, Columbus, Ohio, USA. Dr. Boudoulas is also Director of the Clinical Research Center and President of the Scientific Council of the Biomedical Research Foundation at the Academy of Athens, Athens, Greece.

    CHRISTODOULOS STEFANADIS is Professor of Cardiology and President of the Medical School, The University of Athens, Athens, Greece. In addition, Dr. Stefanadis is Director of the First Department of Cardiology, Hippokration Hospital, Athens, Greece.