Current Research in Pharmaceutical Technology

Current Research in Pharmaceutical Technology

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Summary

Pharmaceutical technology deals with the discovery, production, processing, and safe and effective delivery of medications to patients. Technologies involved include computer modeling for research, bioengineering for research instrumentation, processes and methods for increasing production, and computing technology and biosystematics for the management and analysis of data. This new book covers a wide range of important topics on today’s pharmaceutical technology, such as in vitro drug release and controlled drug delivery, the use of nanotechnology in pharmaceuticals, quantum dot imaging, assessment and efficacy of pharmaceuticals, and much more.

Table of Contents

In Vitro Drug Release Behavior from a Novel Thermosensitive Composite Hydrogel Based on Pluronic F127 and Poly(Ethylene Glycol)-Poly( -Caprolactone)-Poly(Ethylene Glycol) Copolymer. Hydroxycamptothecin-Loaded Nanoparticles Enhance Target Drug Delivery and Anticancer Effect. Pharmaceutical Induction of ApoE Secretion by Multipotent Mesenchymal Stromal Cells (MSCs). Killing Cancer Cells by Targeted Drug Carrying Phage Nanomedicines. Inhibition of Cell Growth and Invasion by Epidermal Growth Factor-Targeted Phagemid Particles Carrying Sirna Against Focal Adhesion Kinase in the Presence of Hydroxycamptothecin. Post-Marketing Assessment of Content and Efficacy of Preservatives in Artemisinin-Derived Antimalarial Dry Suspensions for Paediatric Use. Adenovirus Dodecahedron, as a Drug Delivery Vector. Nanopolymers Improve Delivery of Exon Skipping Oligonucleotides and Concomitant Dystrophin Expression in Skeletal Muscle of mdx Mice. Synthesis of PET-PLA/Drug Nanoparticles and Their Effect with Gold Nanoparticles for Controlled Drug Release in Cancer Chemotherapy. Nanotechnology Approaches to Crossing the Blood-Brain Barrier and Drug Delivery to the CNS. Quantum Dot Imaging for Embryonic Stem Cells. Cationic Nanoparticles for Delivery of Amphotericin B: Preparation, Characterization and Activity In Vitro. Raft-Dependent Endocytosis of Autocrine Motility Factor/Phosphoglucose Isomerase: A Potential Drug Delivery Route for Tumor Cells. Nanotechnology-Based Drug Delivery Systems. Novel Multi-Component Nanopharmaceuticals Derived from Poly(Ethylene) Glycol, Retro-Inverso-Tat Nonapeptide and Saquinavir Demonstrate Combined Anti-HIV Effects. Nanoporous Platforms for Cellular Sensing and Delivery. Skin Permeation Mechanism and Bioavailability Enhancement of Celecoxib from Transdermally Applied Nanoemulsion.

Editor Bio(s)

Professor Sabine Globig received her BA in 1972 at the American University School of International Service and her MS in horticulture and plant physiology in 1988 at Rutgers University, the State University of New Jersey. Presently, she is Professor of Biology at Hazard Community & Technical College in the Appalachian Mountains of eastern Kentucky, where she specializes in human anatomy and physiology and plant sciences. She has also worked as an Adjunct Instructor of Biology at Union County College in New Jersey and at Rutgers University, as well as a certified high school biology teacher. While at Rutgers, she worked as a plant physiology researcher at their AgBiotech Center and held the same position for DNA Plant Technologies Corporation. She has given presentations at XXII International Conference on Horticultural Science, UC Davis, California, 1987; and 1997 International Society for Horticultural Science’s International Symposium on Artificial Lighting in Horticulture, Noordwijkerhout, Netherlands. She has also been included in several Who’s Who entries.

William Hunter, Jr. graduated from Albany College of Pharmacy and has worked for more than 40 years in the pharmaceutical field. He spent the first 17 of those years in community pharmacy and the latter 25 working in a hospital pharmacy. In recent years, in his work at Olean General Hospital, Olean, New York, he has had the opportunity to work with some of the most updated pharmaceutical technology, designed to improve both speed and safety in the distribution of medications, leading the hospital into the 21st century.

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