Early Breast Cancer: From Screening to Multidisciplinary Management, Third Edition

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ISBN 9781841848853
Cat# H100283



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  • Draws on the expertise of leading specialists from three continents
  • Explores the role of the "modern" breast care nurse
  • Covers shared decision-making and informed consent
  • Highlights issues applicable to the current litigious and regulated working environment as well as the web-wise patient
  • Examines aspects of care impacted by the recent economic downturn


Breast cancers are now detected earlier and are thus more likely to be confined to the breast itself and regional nodes. Many of these tumours will have minimal proclivity for hematogenous dissemination and formation of micrometastases. On the other hand, some patients have micrometastatic diseases which can remain dormant and be activated many years after initial diagnosis.

Early Breast Cancer: From Screening to Multidisciplinary Management discusses the principles and practice of breast cancer management with respect to both screen-detected and symptomatic disease. It provides readers with sound understanding and critical insight into many aspects of the disease from epidemiology, genetics, and screening to pathology, diagnosis, treatment, and prevention. This latest edition continues the general ethos of the second edition with an emphasis on early screening and continued development of the multidisciplinary team.

Table of Contents

An Introduction to Screening for Breast Cancer, Linda J. Pointon, Sue K. Down
Mammographic Density as an Early Indicator of Breast Cancer, Jajini Susan Varghese
Genetic Predisposition and Breast Screening, D. Gareth Evans
Application of New Genomic Technologies to Breast Cancer Risk Assessment, Mark Robson
Endocrine Prevention of Breast Cancer, Russell E. McDaniel, V. Craig Jordan

The Biological Basis for Breast Cancer Screening and Its Relevance to Treatment, John R. Benson
Interval Cancers, Anthony J. Maxwell
Survival Advantage of Screen-Detected Cancer over Stage-Matched Symptomatic Cancer, Gordon C. Wishart
Mammography Screening for Women under Age 50, Ismail Jatoi, Pranjali V. Gadgil
Mammographic Screening in Women Aged 50 Years and Above, Chris I. Flowers
The Organization of Breast Screening, Julietta Patnick
Quality Assurance and Evaluation of Outcomes in the NHS Breast Screening Programme, Gill Lawrence

Clinical Assessment of Symptomatic Patients, J. Mathew, K.L. Cheung
Film Reading and Recall from Screening Mammography, Sabrina Rajan, Susan J. Barter, Erika Denton
Radiology of the Normal Breast and Differential Diagnosis of Benign Breast Lesions, Jessica Kuehn-Hajder, Claudia Engeler, Tim Emory
Breast Masses, A. Robin M. Wilson
Asymmetry and Architectural Distortion, Michael J. Michell
The Radial Scar, Sabrina Rajan, Pauline J. Carder
Role of Ultrasound in the Diagnosis of Breast Cancer, Hannah Gay, Steven D. Allen
The Role of MRI in Preoperative Evaluation and Postoperative Follow-Up of Breast Cancer Patients, Richard J. Bleicher
PET Scanning and Breast Cancer Management, Rebecca Wight, Patrick Borgen

Core Biopsy of Breast Lesions, Kathryn Taylor, Peter D. Britton
Vacuum-Assisted Breast Biopsy, Thomas Conner, William The
Preoperative Localization of Impalpable Breast Lesions, Sabrina Rajan, Erika Denton, Susan J. Barter

The Normal Breast and Benign Breast Lesions, Baljit Singh
Histological Risk Factors, Prognostic Indicators, and Staging, Emad A. Rakha, Sarah Pinder, Ian O. Ellis
Premalignant and Borderline Lesions: Ductal and Lobular Carcinoma In Situ, Clive A. Wells, Evdokia Arkoumani
Invasive Breast Carcinoma, Elena Provenzano
Molecular Investigation of Breast Cancer, Paul M. Wilkerson, J.S. Reis-Filho

The Role of Multidisciplinary Teams in Breast Cancer Management, Cath Taylor, Amanda Shewbridge, Massimiliano Cariati, Anand Purushotham
Shared Decision-Making for Breast Cancer Patients, Catharine F. Clay, Alice O. Andrews, Dale Collins Vidal
The Evolving Role of the Breast Care Nurse in the Management of Patients with Early Breast Cancer, Rebecca Llewellyn-Bennett, Jane Barker, Zoë Ellen Winters
Informed Consent in the Management and Research of Breast Cancer, Hazel Thornton

Ductal Carcinoma In Situ of the Breast, Melvin J. Silverstein, Michael D. Lagios
Principles of Surgical Treatment of Invasive Breast Cancer, Starr Koslow, Rache M. Simmons
The Optimum Resection Margin in Breast Conservation Surgery, Lisa Newman, Jessica Bensenhaver
Skin-Sparing Forms of Mastectomy, Gerald Gui
Locoregional Recurrence of Breast Cancer, John R. Benson, Katy Teo
Management of the Axilla I, John R. Benson, Mattia Intra
Management of the Axilla II, Laura Dominici, Mehra Golshan

Radiation Therapy Following Breast Conserving Surgery or Mastectomy, Ian Kunkler
Partial Breast Irradiation, Charlotte Coles, Mukesh Mukesh, Martin Keisch
Targeted Intraoperative Radiotherapy for Breast Cancer: Not All Cancers in the Breast Will Grow, Jayant S. Vaidya, John R. Benson, Jeffrey S. Tobias

Systemic Hormonal Therapies for Early-Stage Breast Cancer, Stephen R.D. Johnston
Adjuvant Chemotherapy and Biological Therapies for Early-Stage Breast Cancer, Sausan Abouharb, Francisco J. Esteva
Primary Systemic Therapy in Breast Cancer, Lisardo Ugidos, Andreas Makris, Jenny C. Chang

Breast Cancer in the Rlderly, R.C.F. Leonard, G.A. Thomas
Breast Cancer and Pregnancy, Christobel Saunders, Angela Ives
Male Breast Cancer, Maisam Z. Fazel, Vassilis Pitsinis
Trends in the Use of Contralateral Prophylactic Mastectomy, Todd M. Tuttle
The Principles of Breast Reconstructive Surgery, Animesh J.K. Patel, Rosanna C. Ching, John R. Benson, Charles M. Malata

Editor Bio(s)

John R. Benson MA DM (Oxon), MD (Cantab), FRCS (Eng), FRCS (Ed), Addenbroke's Hospital, Cambridge, United Kingdom,

Gerald Gui MS, FRCS, FRCS (Ed) Breast Unit, The Royal Marsden, London, United Kingdom

Todd M. Tuttle MD, MPH Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA

Editorial Reviews

Praise for the Previous Editions

"Early breast cancer calls for a specially designed multidisciplinary approach to management, challenging radiologists, surgeons, pathologists, and oncologists to adopt new concepts and strategies. To this end, all the specialized fields involved will benefit from the most comprehensive knowledge currently available on the subject. Early Breast Cancer conveys the relevant data without losing sight of clinical relevance. The information in this book shows how a growing number of patients can profit from timely diagnosis and treatment and substantially increase their chances of surviving breast cancer."
New England Journal of Medicine, September 1999

"The book demands space on many bookshelves, because it is possibly the best reference book to date on the subjects it covers."
New England Journal of Medicine, June 2006