Provides an overview of the latest developments in the study of bicontinuous liquid crystals, categorized by their crystallographic microstructure in equilibriumPresents analytical methods for describing the liquid crystalline phasesDiscusses micro- and macroscopic properties of the phases including aqueous systems and those involving biological lipids, pharmaceutical and biomolecular interactions, polymers and block copolymers, and charged surfactants Describes new techniques that provide insight into the behavior of dispersed cubic and other liquid crystalline phasesExplains how nodal surfaces are used to approximate and plot bicontinuous phase structures and the use of other mathematical tools
With the development of diverse analytical chemistry techniques, the discovery of rich and numerous properties pertaining to bicontinuous liquid crystal structures has yielded beneficial applications in medicine, consumer products, materials science, and biotechnology. Presenting contributions from 24 experts worldwide, Bicontinuous Liquid Crystals presents a comprehensive overview of these structures with a practical approach to applying them in manufacturing and laboratory processes.
This book considers the cubic, mesh, ribbon, and sponge equilibrium phases of bicontinuous structures. It begins with a historical perspective and a theoretical platform for study, followed by a detailed discussion of physical chemistry, properties, and structural characteristics of the different phases. The text interrelates the most useful analytical methods for the characterization of the behavior and stability of liquid crystalline phases based on structure, geometry, composition-dependent changes, temperature, dispersion, and other factors. These techniques include differential geometry, thermodynamics, local and global packing, and the study of conformational entropy. The book also highlights tools for mathematically visualizing bicontinuous systems. This provides an excellent foundation for the authors' examination of the latest studies and applications, such as controlled release, materials development, fabrication, processing, polymerization, protein crystallization, membrane fusion, and treatment of human skin.
Bicontinuous Liquid Crystals represents current trends and innovative ideas in the study of bicontinuous liquid crystals. Divided into three sections, it provides a complete overview of theoretical and modeling aspects, physical chemistry and characterization, and applications in this active field of research.
Table of Contents
Bicontinuous Cubic Liquid Crystalline Materials: A Historical Perspective and Modern Assessment; Kåre Larsson
Intermediate Phases; Michael C. Holmes and Marc S. Leaver
Cubic Phases and Human Skin: Theory and Practice; Steven Hoath and Lars Norlén
The Relationship between Bicontinuous Inverted Cubic Phases and Membrane Fusion; D.P. Siegel
Aspects of the Differential Geometry and Topology of Bicontinuous Liquid-Crystalline Phases; Robert W. Corkery
Novel L3 Phases and Their Macroscopic Properties; R. Beck and H. Hoffmann
Bicontinuous Cubic Phases of Lipids with Entrapped Proteins: Structural Features and Bioanalytical Applications; Valdemaras Razumas
NMR Characterization of Cubic and Sponge Phases; Olle Söderman and Björn Lindman
Synthesis of Controlled-Porosity Ceramics Using Bicontinuous Liquid Crystals; Stephen E. Rankin
Controlled Release from Cubic Liquid-Crystalline Particles (Cubosomes); Ben J. Boyd
Membrane Protein Crystallization in Lipidic Bicontinuous Liquid Crystals; Martin Caffrey
Application of Monoglyceride-Based Liquid Crystals as Extended-Release Drug Delivery Systems; Chin-Ming Chang and Roland Bodmeier
Cubic Liquid-Crystalline Particles as Protein and Insoluble Drug Delivery Systems; Hesson Chung, Seo Young Jeong, and Ick Chan Kwon
Bicontinuous Liquid Crystalline Mesophases-Solubilization Reactivity and Interfacial Reactions; Nissim Garti
Applications of Lipidic Cubic Phases in Structural Biology; Ehud M. Landau
The Controlled Release of Drugs from Cubic Phases of Glyceryl Monooleate; Jaehwi Lee and Ian W. Kellaway