Introduction to Environmental Toxicology: Impacts of Chemicals Upon Ecological Systems, Third Edition

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ISBN 9781566706605
Cat# L1660
 

Features

  • Serves as a landmark in the development of environmental toxicology as a distinct field
  • Addresses the impacts of chemicals on an ecological system as a whole, instead of on individual organisms
  • Incorporates a revised perspective on how ecosystems operate, accounting for hierarchies of spatial and temporal scale, and patch dynamics
  • Summary

    The rapidly evolving field of environmental toxicology involves the study of toxic compounds and their effect on living organisms, as well as their fate within the natural environment. Since publication of the first edition, Introduction to Environmental Toxicology has found a secure place among the major texts and references in this field.

    Introduction to Environmental Toxicology, Third Edition seamlessly covers processes and impacts from the molecular level all the way up to population levels. While retaining the strengths of previous editions, the third edition includes a new chapter on fluoride, an update on endocrine disruption, a discussion of the use of models to reconstruct concentration-response curves, expansion of the metals chapter, and new developments in ecological risk assessment for management decisions at site to regional scales. It is an ideal text for introducing students to the fields of ecotoxicology and risk assessment.

    Table of Contents

    INTRODUCTION TO ENVIRONMENTAL TOXICOLOGY AND ITS ROLE IN ENVIRONMENTAL DECISION MAKING
    Environmental Toxicology as an Interdisciplinary Science
    A Brief History of and Organizations in Environmental Toxicology
    Interactions and Connections of Environmental Toxicology to the Management of Ecological Systems
    Legislation
    Use of Models in Environmental Science
    Introduction to the Textbook
    References
    Study Questions

    A FRAMEWORK FOR ENVIRONMENTAL TOXICOLOGY
    Classical Viewpoint for Classifying Toxicological Effects
    Alternative Framework Incorporating Complexity Theory
    Spatial and Temporal Scales
    Combining Scale and Ecological Dynamics:The Hierarchical Patch Dynamic Paradigm
    References and Suggested Readings
    Study Questions

    AN INTRODUCTION TO TOXICITY TESTING
    The Dose-Response Curve
    Standard Methods
    Classification of Toxicity Tests
    Design Parameters for Single Species Toxicity Tests
    Overview of Available Statistical Methods for the Evaluation of Single-Species Toxicity Tests
    The Design of Multispecies Toxicity Tests
    Summary of Design Guidelines for Multispecies Toxicity Tests
    References and Suggested Readings
    Study Questions

    SURVEY AND REVIEW OF TYPICAL TOXICITY TEST METHODS
    Single Species Toxicity Tests
    Animal Care and Use Considerations
    Multispecies Toxicity Tests
    Summary
    References and Suggested Readings
    Study Questions
    Appendix: The Natural History and Utilization of Test Species

    ROUTES OF EXPOSURE AND MODES OF ACTION
    The Damage Process
    Atmospheric Pollutants and Plants
    Mechanisms of Action
    Common Modes of Action in Detail
    Introduction to QSAR
    Receptor Mediated Toxicity, Endocrine Disruption, and a Mechanistic SAR Analysis of PCB Toxicity
    References and Suggested Readings
    Study Questions

    FACTORS MODIFYING THE ACTIVITY OF TOXICANTS
    Introduction
    Physicochemical Properties of Pollutants
    Environmental Factors
    Interaction of Pollutants
    Toxicity of Mixtures
    Mixture Estimation System 11
    Estimating the Toxicity of Polynuclear Aromatic Hydrocarbons
    Biological Factors Affecting Toxicity
    References and Suggested Readings
    Study Questions

    INORGANIC GASEOUS POLLUTANTS
    Sulfur Oxides
    Nitrogen Oxides
    Ozone
    Carbon Monoxide
    References and Suggested Readings

    FLUORIDE AS A CONTAMINANT OF DEVELOPING ECONOMIES
    Environmental Sources and Forms Of Fluoride
    Industrial Sources of Fluoride Pollution
    Effects On Plants
    Effects on Animals
    Effects On Human Health
    Biochemical Effect
    References and Suggested Readings
    Study Questions

    HEAVY METALS
    Lead
    Cadmium
    Mercury
    Study Questions
    References and Suggested Readings

    BIOTRANSFORMATION, DETOXIFICATION, AND BIODEGRADATION
    Introduction
    Metabolism of Environmental Chemicals: Biotransformation
    Microbial Degradation
    Bioremediation
    Isolation and Engineering of Degradative Organisms
    The Genetics of Degradative Elements
    An Example of a Detoxification Enzyme-the OPA Anhydrolases
    References and Suggested Readings
    Study Questions

    Measuring and Predicting the Responses of Ecological Systems to Toxicants
    Introduction
    Measurement of Ecological Effects at Various Levels of Biological Organization
    Molecular and Physiological Indicators of Chemical Stress Biomarkers
    Population Parameters
    Assemblage and Community Parameters
    Interpretation of effects at the Population, Community and Ecosystem Levels
    of Organization
    Community and Ecosystem Effects
    Application of Multivariate Techniques
    Pollution-Induced Community Tolerance
    Interpretation of Ecosystem Level Impacts
    An Alternative Model: The Community Conditioning Hypothesis
    The Problem of the Reference Site
    References and Suggested Readings
    Study Questions

    ECOLOGICAL RISK ASSESSMENT
    Introduction
    Basics of Risk Assessment
    Ecological Risk Assessment
    Ecological Risk Assessment Framework
    Risk Characterization
    Developments in Ecological Risk Assessment
    A Ranking Approach to Multiple Stressor, Wide Area Ecological Risk Assessment
    A General Model For Regional Risk Assessment - The Ten Steps
    Life Cycle Assessment as a Decision Making Tool
    References and Suggested Readings
    Study Questions

    Appendices
    Index

    Editorial Reviews

    About the second edition:
    "Buy the book, read it, and learn from it. This book genuinely helps to unify and clarify the ecotoxicology field, and as such joins a select few titles bringing coherence to a complex scientific arena. I hope that the authors will keep carefully revised and updated editions in circulation for many years to come."
    - P.G. Wells, Environmental Conservation Branch, Environment Canada, in Ecotoxicology, Vol. 9, No.3

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