1st Edition

Biotechnology in Medical Sciences

By Firdos Alam Khan Copyright 2014
    496 Pages 124 Color Illustrations
    by CRC Press

    496 Pages 124 Color Illustrations
    by CRC Press

    As the field of medical biotechnology grows with new products and discoveries, so does the need for a holistic view of biotechnology in medicine. Biotechnology in Medical Sciences fulfills that need by delivering a detailed overview of medical biotechnology as it relates to human diseases and epidemiology, bacteriology and antibiotics, virology and vaccines, immunology and monoclonal antibodies, recombinant DNA technology and therapeutic proteins, stem cell technology, tissue engineering, molecular diagnostics and forensic science, gene therapy, synthetic biology and nanomedicine, pharmacogenomics, bioethics, biobusiness and intellectual property rights, and career opportunities.

    Organized to follow the chronology of major medical biotechnology research, breakthroughs, and events, this first-of-its-kind text:

    • Covers all aspects of medical biotechnology, from labs to clinics and basic to advanced applications
    • Describes historical perspectives and modern discoveries in medical biotechnology
    • Explains how various biotechnology products are used to treat and prevent disease
    • Discusses the tools and techniques currently employed in medical biotechnology
    • Includes a bibliography at the end of each chapter to encourage further study

    Complete with colorful illustrations and examples, Biotechnology in Medical Sciences provides a comprehensive yet accessible treatment of this growing field.

    Introduction to Medical Biotechnology

    Definition of Medical Biotechnology

    Historical Perspectives of Medical Biotechnology

    Discoveries Made in Medical Biotechnology

    Important Products of Medical Biotechnology

    Tools of Medical Biotechnology

    Career Opportunities

    Current Research Trends

    References and Reading

    Human Diseases and Epidemiology

    Definition and Terminology of Human Disease

    Types of Human Diseases

    Prevalence and Causes of Human Diseases

    Stages of Diseases

    Disease Transmission

    Epidemiology

    Diagnostic Tools and Techniques

    Current Research Trends

    References and Reading

    Bacteriology and Antibiotics

    Microbes: Structure, Types, and Function

    Human Diseases Caused by Microbes

    Applications of Microbes in Medicine

    Applications of Microbes in Food and Dairy Products

    Development of Anti-Microbial Drugs

    Challenges and Hurdles in Treating Microbial Infections

    Current Research Trends

    References and Reading

    Virology and Vaccines

    Viruses: Structure, Classification, and Function

    Human Diseases Caused by Viruses

    Mechanism of Viral Replication in the Host

    Applications of Viruses in Medicine

    Vaccines and Anti-Viral Drugs

    Development of Vaccines and Anti-Viral Drugs

    Challenges and Hurdles in Treating Viral Infections

    Current Research Trends

    References and Reading

    Immunology and Monoclonal Antibodies

    Immunity and Immune Disorders

    Significance of Monoclonal Antibodies

    Applications of Monoclonal Antibodies

    Immunotechnology and Immunodiagnostics

    Development and Production of Monoclonal Antibodies

    Challenges and Hurdles in Monoclonal Antibodies

    Current Research Trends

    References and Reading

    Recombinant DNA Technology and Therapeutic Proteins

    Definition and Significance of rDNA Technology

    Making of rDNA Products

    Applications of rDNA Technology

    Disease-Associated Protein Dysfunctions

    Significance of Therapeutic Proteins

    Current Research Trends

    References and Reading

    Stem Cell Technology

    Definition and Significance of Stem Cells

    Types and Classifications of Stem Cells

    Applications of Stem Cells

    Stem Cell-Based Therapy: Clinical Trials

    Stem Cell-Based Therapy: Animal Trials

    Stem Cells and Drug Testing

    Stem Cell Lines and Banks

    Challenges and Hurdles in Stem Cell Research

    Current Research Trends

    References and Reading

    Tissue Engineering

    Definition and Significance of Tissue Engineering

    Applications of Tissue Engineering

    Tools and Techniques of Tissue Engineering

    Tissue-Engineered Products

    Challenges and Hurdles in Tissue Engineering

    Current Research Trends

    References and Reading

    Molecular Diagnostics and Forensic Science

    Significance of Molecular Diagnostics

    Genetic Diseases Profiling

    DNA Fingerprinting

    Forensic Science

    Diagnostic Tools and Techniques

    Ethical Issues in Genetic Profiling

    Current Research Trends

    Gene Therapy

    Definition of Gene Therapy

    Genetic Disorders and Prevalence

    Applications of Gene Therapy

    Clinical Trials Based on Gene Therapy

    Challenges and Hurdles Associated with Gene Therapy

    Tools and Techniques Used in Gene Therapy

    Current Research Trends

    References and Reading

    Synthetic Biology and Nanomedicine

    Definition of Synthetic Biology and Nanomedicine

    Applications of Synthetic Biology in Medicine

    Tools of Synthetic Biology

    Applications of Nanomedicine

    Tools of Nanomedicine

    Challenges and Hurdles in Synthetic Biology and Nanomedicine

    Current Research Trends

    References and Reading

    Pharmacogenomics

    Definition and Significance of Pharmacogenomics

    Adverse Drug Reactions and Causes

    Applications of Pharmacogenomics

    Success stories of Pharmacogenomics

    Challenges and Hurdles in Pharmacogenomics

    Tools of Pharmacogenomics

    Current Research Trends

    References and Reading

    Bioethics

    Definition of Bioethics

    Historical Perspectives of Bioethics

    Major Bioethical Issues

    Bioethical Issues and Biotechnology Industry

    References and Reading

    Biobusiness and Intellectual Property Rights

    What Is Biobusiness?

    Components of Biotechnology Industry

    Investment and Finance

    Regulatory Affairs and Compliance Issues in Biobusiness

    Patents and IPRs

    Mergers and Acquisitions

    Market Trends and Future Directions

    References and Reading

    Career Opportunities

    Challenging Job Opportunities

    Jobs in Biotechnology: World Scenario

    Academic Jobs versus Corporate Jobs

    Classification of Jobs

    References and Reading

    Biography

    Firdos Alam Khan holds a doctoral degree from Nagpur University, India. He possesses over 20 years of research and teaching experience gained from his service at the National Centre for Biological Sciences, Bangalore, India; Massachusetts Institute of Technology, Cambridge, USA; Reliance Life Sciences, Mumbai, India; and Manipal University, Dubai, UAE—where he is currently a professor and chairperson of the School of Life Sciences (previously known as the Department of Biotechnology). Widely published, he has been associated with the International Brain Research Organization, France and Society for Neuroscience, USA. A popular conference presenter, Dr. Khan specializes in neuroscience, pharmacology, and stem cell biotechnology—in which he holds two US patents.

    "This textbook provides comprehensive coverage of biotechnology as applied to medical sciences. It has a good number of figures that are clearly presented to engage the reader. Each chapter summarises the key researchers in the field and their achievements, which is useful. The chapters on ethics, business, and careers are also valuable sections."
    —Dr. Aysha Divan, University of Leeds, UK

    "… an abundance of small pills of knowledge that give a broad view of this topic. … This book not only presents the latest developments in basic biotechnology but also covers other less common aspects."
    —Javier García-Castro, Instituto de Salud Carlos III, Madrid, Spain

    "If you read this book cover to cover, you will learn a lot about different aspects of biotechnology in medical sciences. The engaged reader will make considerable headway with this book even outside the medical setup. … [The book] is an anthology of different facets that collectively constitute the field of medical biotechnology."
    —Dr. Matin Ahmad Khan, Mahatma Gandhi Memorial Medical College, Jamshedpur, India

    "… could be used as an additional book for an undergraduate biotechnology course or as an introductory book for a graduate student or researcher crossing over into medical biotechnology. … a good reference book for students interested in learning more about medical biotechnology. … a good introduction for someone not familiar with the field."
    —Alexandra Gorgevska, Ph.D, Palm Beach State College, Palm Beach Gardens, Florida, USA