Endothelial Cell Plasticity in the Normal and Injured Central Nervous System

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ISBN 9781466599215
Cat# K20941



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  • Presents essential information for practitioners in diverse fields including neurologists, gerontologists, and oncologists
  • Addresses neurodegenerative diseases such as Parkinson’s and Alzheimer’s as well as epilepsy and spinal injury
  • Covers new areas of investigation into endothelial cell plasticity


This book is designed to highlight the importance of endothelial cells as key players in the functioning of the nervous system under both normal and pathological conditions. The book demonstrates that endothelial cells are an essential and dynamic cell population in the central nervous system, with multiple and complex roles, not only in the maintenance of homeostasis, but also in the regulation of important processes. These include neurogenesis, neural control of reproduction, aging, neurodegeneration, and tumor invasion. The book exhaustively reviews the newest findings in this exciting new area of investigation.

Table of Contents

Embryonic Development of the Brain Vascular System
Endothelial Cells and Maintenance of Neurogenic Niches during Embryonic Development and Adult Life
Alterations of Brain Endothelial Cells in Drug-Resistant Epilepsy: Drug Transporters
Dynamic Control of Endothelial Cells in Neural Reproduction Centers
Blood Vessel Remodeling After Stroke
Systemic Vascular Alterations and Neurodegenerative Diseases
Endothelial Cells, Alzheimer Disease and Metabolic Syndrome
Micro-Vascular Dysfunction After Spinal Cord Injury
Angiogenesis During Tumor Proliferation and Cell Invasion
Neuronal-Glial-Endothelial Interactions Regulate Central Nervous System Homeostasis