DNA Repair and Cancer: From Bench to Clinic

Srinivasan Madhusudan, David M. Wilson III

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January 22, 2013 by CRC Press
Reference - 718 Pages - 18 Color & 56 B/W Illustrations
ISBN 9781466577435 - CAT# K16791

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Summary

DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.