A comprehensive update to this preeminent and accessible text, this fifth edition of a bestseller was developed as a response to man's attempts to climb unaided to higher altitudes and to spend more time in these conditions for both work and recreation. It describes the ever-expanding challenges that doctors face in dealing with the changes in human physiology and particular medical conditions that arise from exposure to altitude and cold.
The highly respected authors of this fifth edition are internationally recognized for their academic research in the field, and are all experienced mountaineering physicians who have dealt with illness and accidents in high places. They continue to provide a text that will help physicians to improve the health and safety of all people who visit, live, or work in cold and thin air conditions experienced in high mountains.
High Altitude Medicine and Physiology is invaluable for any doctor accompanying an expedition or advising patients on a visit to high altitudes, physicians specializing in illness and accidents in high places, and physiologists who study our dependence on oxygen and the adaptation of the body to altitude.
Geography and the human response to altitude
Genetics at high altitude
Altitude acclimatization and deterioration
Control of breathing at high altitude
Pulmonary gas exchange
Blood-gas transport and acid-base balance
Limiting factors at extreme altitude
Nutrition, metabolism and intestinal function
Endocrine and renal systems at altitude
Central nervous system
High altitude populations
Acute mountain sickness
High altitude cerebral edema
High altitude pulmonary edema
Chronic mountain sickness and high altitude pulmonary hypertension
Other altitude-related conditions: thromboembolemic diseases, neurologic conditions, ophthalmologic conditions, altitude cough, anesthesia at altitude
The physiology and medical aspects of heat and cold
Pre-existing medical conditions at altitude
Women at altitude
Extremes of age at altitude: children and the elderly
Commercial, scientific and military activities at high altitude
Athletes and altitude
John B. West MD PhD DSc FRCP FRACP, Professor of Medicine & Physiology, the School of Medicine, University of California, San Diego, USA
Robert B. Schoene MD, Clinical Professor of Medicine, the School of Medicine, University of California, San Diego, USA
James S. Milledge Md FRCP, Formerly Consultant Respiratory Physician and Medical Director, Northwick Park Hospital, Harrow, UK
Andrew Luks, Assistant Professor, Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, USA
Praise for Previous Editions:
"... rigorously updated with several new additions, including sections on women and children at high altitude, neurological disorders, athletic training to prepare for altitude and more. All of which will undoubtedly help doctors stay abreast of this continually changing area of specialism."
—The Geographical Magazine
"With this edition, High Altitude Medicine and Physiology retains its place as the leading scholarly text on the subject."
—Ken Zafren, Wilderness and Environmental Medicine
"… a definitive text on the subject. … These are the world's experts, and I admit, my role models in so many ways. Therefore, it is an honor to review (and recommend) this book. … The coverage in this volume is extensive and, for a wilderness medicine enthusiast such as me, quite fascinating. I am particularly appreciative for the innovative discussions of such topics as 'History,' 'Commuting to high altitude for commercial and other activities,' 'Athletes and altitude,' and 'Practicalities of field studies.' … The litmus test question is whether it is sufficiently improved over the previous edition to warrant its purchase. In my opinion, the answer is a resounding, 'Yes!'"
—Dr. Paul S. Auerbach, leading authority on wilderness medicine
"... a definitive text. It should be the first port of call for anyone with medical training and an interest in high-altitude physiology or indeed planning to travel to high altitude, to gain an understanding of the associated physiological changes. ... it does contain the core principles of physiology and medicine on which these areas of medical interest are based."
—Tim Clark in Annals of the Royal College of Surgeons of England