This two-volume set contains two books: The Techniques of Non-Clinical Vascular Infusion Technology, Second Edition and The Science of Non-Clinical Vascular Infusion Technology. The first volume provides complete instructions for a wide range of infusion techniques delivered to multiple species. With sections devoted to rats, mice, rabbits, dogs, minipigs, nonhuman primates, and juvenile animals, this thorough text gives step-by-step instructions for the use of a variety of techniques and equipment. The second volume brings together the knowledge underlying practices from around the world to help refine the procedures and enhance the understanding of infusion technology.
The Techniques of Non-Clinical Vascular Infusion Technology, Second Edition:
Rat
Mouse
Dog
Primate
Rabbit and Reproductive Studies
Minipig
Juvenile Animals
The Science of Non-Clinical Vascular Infusion Technology:
Body Fluid Dynamics
Composition. Compartmentalization and Distribution. Movement between Compartments/Exchange. Body Fluid Homeostasis.
Physico-Chemical Properties
Osmolality. Acid/Base Balance. Viscosity. Surface Tension.
Vascular Infusion Dynamics
Rates of Delivery. Infusion Volumes. Blood Pressure and Flow Rates.
Formulation Chemistries and Their Effects
Sodium (Na). Chloride (CI). Calcium (Ca). Potassium (K). Phosphate (PO). DMSO. Glucose. Dextrose. Sodium Hydroxide (Naoh). Hydrogen Chloride (HCI). Amino Acids. Proteins. Lipids. Pegs. Cyclodextrins. HPMC.