Medical Imaging: Principles and Practices

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ISBN 9781439871027
Cat# K13254



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ISBN 9781439871034
Cat# KE13422



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  • Provides a detailed overview of x-ray imaging and computed tomography
  • Covers the fundamental concepts in signal acquisition and processing used in MRI and magnetic resonance microscopy
  • Discusses the physics of instrumentation and signal collection for nuclear medicine and its application in clinical practice
  • Includes emerging technologies for in vivo imaging, such as electrical impedance tomography (EIT)
  • Contains an overview of recent developments in the use of MRI for vascular imaging and its key advantages over ultrasound-based approaches
  • Examines dynamic contrast-enhanced MRI, a critical method for the analysis of oncologic tumor and its response to antiangiogenic class of therapeutics
  • Highlights the modeling of myocardial deformation to better understand cardiac function and associated anomalies
  • Includes detailed chapters on utility of MRI for cardiovascular imaging
  • Offers a comprehensive overview of osteoarthritis (OA), various MR approaches for imaging knee, and methods for quantitative image analysis
  • Provides comprehensive overview various approaches for medical imaging data mining and search


The discovery of x-ray, as a landmark event, enabled us to see the "invisible," opening a new era in medical diagnostics. More importantly, it offered a unique undestanding around the interaction of electromagnetic signal with human tissue and the utility of its selective absorption, scattering, diffusion, and reflection as a tool for understanding the physiology, evolution of disease, and therapy. With contributions from world-class experts, Medical Imaging: Principles and Practices offers a review of key imaging modalities with established clinical utilization and examples of quantitative tools for image analysis, modeling, and interpretation.

The book provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in Magnetic Resonance Microcopy, the physics of instrumentation and signal collection, and their application in clinical practice. Highlights include a chapter offering a unique perspective on the use of quantitative PET for its applications in drug discovery and development, which is rapidly becoming an indispensible tool for clinical and research applications, and a chapter addressing the key issues around organizing and searching multimodality data sets, an increasingly important yet challenging issue in clinical imaging.

Topics include:

  • X-ray imaging and computed tomography
  • MRI and magnetic resonance microscopy
  • Nuclear imaging
  • Ultrasound imaging
  • Electrical Impedance Tomography (EIT)
  • Emerging technologies for in vivo imaging
  • Contrast-enhanced MRI
  • MR approaches for osteoarthritis and cardiovascular imaging
  • PET quantitative imaging for drug development
  • Medical imaging data mining and search

The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community ofresearchers and practitioners.

Table of Contents

Mammography, Martin J. Yaffe
Computed Tomography, Ian A. Cunningham and Philip F. Judy
Magnetic Resonance Imaging, Steven Conolly, Albert Macovski, John Pauly, John Schenck, Kenneth K. Kwong, David A. Chesler, Xiaoping Hu, Wei Chen, Maqbool Patel, and Kamil Ugurbil
Nuclear Medicine, Barbara Y. Croft and Benjamin M.W. Tsui
Ultrasound, Richard L. Goldberg, Stephen W. Smith, Jack G. Mottley, and K. Whittaker Ferrara
Magnetic Resonance Microscopy, Xiaohong Zhou and G. Allan Johnson
Positron-Emission Tomography, Thomas F. Budinger and Henry F. VanBrocklin
Electrical Impedance Tomography, N. Huber, W. Wang, and D.C. Barber
Magnetic Resonance Imaging of Atherosclerosis, Chun Yuan, William S. Kerwin, Gador Canton, Jinnan Wang, Huijun Chen, and Niranjan Balu
Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Edward Ashton and Vijay Shah
MRI of Myocardial Deformations: Imaging and Modeling, Hui Wang and Amir A. Amini
MRI for OA Diagnosis and Drug Development, Saara Totterman and José G. Tamez-Peña
Utility of PET in Pharmaceutical Development, R. Boellaard, M. Lubberink, and R.P. Maguire
Medical Image Search, Thomas Deserno