The Nanobiotechnology Handbook

The Nanobiotechnology Handbook

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Features

  • Draws on the expertise of world class contributors from a number of different countries
  • Provides a thoroughly comprehensive overview of all major aspects of nanobiotechnology
  • Details the role of nanobiotechnology in bioanalysis and bioprocessing
  • Covers the use of nanotechnology in biomedicine
  • Presents the educational and work force development in nanobiotechnology
  • Offers extensive references within each chapter to facilitate further study

Summary

A thorough overview of nanobiotechnology and its place in advances in applied science and engineering, The Nanobiotechnology Handbook combines contributions from physics, bioorganic and bioinorganic chemistry, molecular and cellular biology, materials science, and medicine as well as from mechanical, electrical, chemical, and biomedical engineering to address the full scope of current and future developments. World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular and biomedical nanotechnology, biosensors, biocatalysis and biofuel, and education and workforce development. It includes a companion CD that contains all figures in the book.

The book begins with discussions of biomimetic nanotechnology, including a comprehensive overview of DNA nanostructure and DNA-inspired nanotechnology, aptamer-functionalized nanomaterials as artificial antibodies, artificial enzymes, molecular motors, and RNA structures and RNA-inspired nanotechnology. It shows how nanotechnology can be inspired by nature as well as adverse biological events in diagnostic and therapeutic development. From there, the chapters cover major important and widely used nanofabrication techniques, applications of nanotechnology for bioprocessing followed by coverage of the applications of atomic force microscopy (AFM), optical tweezers and nanofluidics as well as other nanotechnology-enabled biomolecular and cellular manipulation and detection.

Focusing on major research trends, the book highlights the importance of nanobiotechnology to a range of medical applications such as stem cell technology and tissue engineering, drug development and delivery, imaging, diagnostics, and therapeutics. And with coverage of topics such as nanotoxicity, responsible nanotechnology, and educational and workforce development, it provides a unique overview and perspective of nanobiotechnology impacts from a researcher’s, entrepreneur’s, economist’s and educator’s point of view. It provides a resource for current applications and future development of nanobiotechnology.

Table of Contents

Part I Biomimetic Nanotechnology

DNA Nanostructures
Marya Lieberman

Aptamer-Functionalized Nanomaterials for Cell Recognition
Jing Zhou and Yong Wang

Artificial Enzymes
James A. Stapleton, Agustina Rodriguez-Granillo, and Vikas Nanda

Molecular Motors
Timothy D. Riehlman, Zachary T. Olmsted, and Janet L. Paluh

From RNA Structures to RNA Nanomachines
Sabarinath Jayaseelan, Paul D. Kutscha, Francis Doyle, and Scott A. Tenenbaum

DNA Damage Response Research, Inherent and Future Nano-Based Interfaces for Personalized Medicine
Madhu Dyavaiah, Lauren Endres, Yiching Hsieh, William Towns, and Thomas J. Begley

Virus-Based Nanobiotechnology
Magnus Bergkvist and Brian A. Cohen

Biomimetic Nanotopography Strategies for Extracellular Matrix Construction
Esther Lee and Kam W. Leong

Butterfly Wing–Inspired Nanotechnology
Rajan Kumar, Sheila Smith, James McNeilan, Michael Keeton, Joseph Sanders,

Alexander Talamo, Christopher Bowman, and Yubing Xie

Receptor-Based Biosensors: Focus on Olfactory Receptors and Cell-Free Sensors
Nadine Hempel

Part II Nanobiofabrication


Microcontact Printing
Jingjiao Guan

Electron Beam Lithography for Biological Applications
John G. Hartley

Laser Direct-Write
Timothy Krentz, Theresa Phamduy, Brian Riggs, Brian Ozsdolay, and Douglas B. Chrisey

Electrospinning of Nanofibers
Andrea M. Unser and Yubing Xie

Part III Nanobioprocessing

Applications of Nanotechnology to Bioprocessing
Susan T. Sharfstein and Sarah Nicoletti

Part IV Biomolecular and Cellular Manipulation and Detection

Atomic Force Microscopy
Gunjan Agarwal and Tanya M. Nocera

Dielectrophoresis
Shiqing Wu and Shengnian Wang

Nanofluidics
Xin Hu and Weixiong Wang

Optical Tweezers
Yingbo Zu, Fangfang Ren, and Shengnian Wang

Cellular Response to Nanoscale Features
Manus J.P. Biggs, Matthew J. Dalby, and Shalom J. Wind

Micro- and Nanotechnologies in Integrative Biology
Xulang Zhang

Part V Biomedical Nanotechnology

Micro- and Nanotechnology in Tissue Engineering
Jane Wang, Robert Langer, and Jeffrey T. Borenstein

Nanotechnology in Drug Delivery
Jungmin Cho, Sungwon Kim, and Kinam Park

Lipid-Based Nanoparticles for siRNA Delivery
Bo Yu, L. James Lee, and Robert J. Lee

Nanodiamonds for Bioimaging and Therapeutic Applications
V. Vaijayanthimala, Yuen Yung Hui, and Huan-Cheng Chang

Biomedical Micro-Probe for Super Resolved Image Extraction
Asaf Shahmoon, Shiran Aharon, Dror Fixler, Hamutal Slovin, and Zeev Zalevsky

Part VI Nanobiotechnology Impacts

Nanotoxicity
Rui Chen and Chunying Chen

Responsible Nanotechnology: Controlling Exposure and Environmental Release via Rational Design
Nathaniel C. Cady and Aaron D. Strickland

Educational and Workforce Development in Nanobiotechnology
Laura I. Schultz and Daniel D. White

Index

Author Bio(s)

Editorial Reviews

"…World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular and
biomedical nanotechnology, biosensors, biocatalysis and biofuel, and education and
workforce development. …The Nanobiotechnology Handbook highlights the
importance of nanobiotechnology to a range of medical applications such as stem cell
technology and tissue engineering, drug development and delivery, imaging, diagnostics,
and therapeutics. And with coverage of topics such as nanotoxicity, responsible
nanotechnology, and educational and workforce development, it provides an overview
and perspective of nanobiotechnology impacts from a variety of professional points of
view."
––SirReadaLot.org

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