Written to meet the needs of sophomore students in biomedical engineering courses, this textbook covers the span of biomedical engineering from the basic life sciences to practical clinical applications. Primary consideration is given to biomaterials, biomechanics, instrumentation, imaging, and clinical biomedical engineering, but other topics are discussed as well. It offers many illustrations and graphics within the chapters to clarify concepts and facts. Sidebar descriptions of biomedical engineering careers related to the text section are provided as well. This textbook also includes many homework and discussion problems. A solutions manual is provided as well, upon qualification.
Prologue (Introduction)
What is BME?
Subfields of BME
Types of careers in BME
Places of employment in BME
Training of Biomedical Engineers
Information sources for biomedical engineering
Ethics in biomedical engineering
Introductory biology for biomedical engineers
Modern biology
Molecular biology
Cellular biology
Tissue biology
Organisms
Sidebar: ethics in modern biology
Physiological modeling
Definition of a physiological model
Model complexity
Model types
Process of modeling
Example of arterial compliance
Example of drug in cardiovascular system
Finite element model
Biomaterials
Biomaterials defined
Material properties
Tissue response to foreign materials
Regulatory and ethical issues
Selection of implant materials
Sidebar: Career examples in biomaterials
Sidebar: ethics in biomaterials - silicone breast implants
Tissue engineering - regenerative medicine
Definition of tissue engineering
Internal and extra corporeal engineered organs
Growing replacement tissues and organs
Problems of scale
Still in the research stage
Examples currently being developed
Sidebar: Career examples in tissue engineering
Biomechanics
Definition of biomechanics
Musculoskeletal system
Review of Newton's laws of motion
Musculoskeletal statics
Musculoskeletal dynamics
Strength of biological materials
Mechanobiology
Human motion analysis - the gait laboratory
Sidebar: Career examples in biomechanics
Sidebar: Ethical case in biomechanics
Artificial organs
Definition
Example of an external device - artificial kidney
Example of an internal device - cardiac assist device
Significant problems to be overcome with artificial organs
Sidebar: Career examples in artificial organs
Sidebar: Ethical decisions in artificial organs - who gets the device?
Bioinstrumentation
Fundamental medical instrumentation system
Measurement fundamentals
Sensors and transducers
Signal processing
Wireless transmission
Data display and storage
Examples of instrumentation systems
Sidebar: Career examples in biomedical instrumentation
Sidebar: Ethics in bioinstrumentation - health monitoring and invasion of privacy
Medical imaging
Overview
Ultrasound
X-ray
Magnetic Resonance Imaging
Nuclear medicine imaging
Risks of imaging devices
Filmless radiology
Molecular imaging
Sidebar: Career examples in medical imaging
Sidebar: Ethics in medical imaging
Biomedical computing
Application of computing technology to clinical medicine
Medical informatics
Picture (image) archiving technology
Computerized interpretation of medical data
Career examples in biomedical computing (sidebar)
Biomedical engineering in the clinic
Special roles for biomedical engineers in the hospital
Clinical engineering
Rehabilitation engineering
Sidebar: Career examples for biomedical engineers in the clinic
Sidebar: Ethics in clinical medicine - therapeutic value versus safety
Epilogue
Biomedical engineering is a broad, interdisciplinary field
Increasing opportunities for employment and economic growth
Engineering and technology offer opportunities for new, quantitative understanding of fundamental life science and disease as well as treatment of disease
Biomedical engineer must, as the physician, do no harm
Biomedical engineering is an exciting frontier in biology, medicine and engineering
Michael Neuman, Ph.D., MD is Professor and Chair of the Department of Biomedical Engineering at Michigan Technological University, in Houghton.