Handbook of Lipid Bilayers, Second Edition

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ISBN 9781420088328
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Features

  • Offers extensive updates with more than double the amount of data
  • Includes more detailed introductory sections that explain important concepts and provide a broader framework for understanding the data
  • Contains entirely new sections covering cholesterol phase diagrams, hydration isotherms, spontaneous curvature, and cubic phases
  • Presents much expanded information on glycolipids, including now chapters on elastic constants, densitometry and non-lamellar phases

Summary

Now in its second edition, the Handbook of Lipid Bilayers is a groundbreaking work that remains the field’s definitive text and only comprehensive source for primary physicochemical data relating to phospholipid bilayers. Along with basic thermodynamic data, coverage includes both dynamic and structural properties of phospholipid bilayers. It is an indispensable reference for users of bilayer model membranes and liposome delivery systems and for those interested in the biophysics of membrane structure.

Each chapter in the second edition contains considerable amounts of explanation and elaboration, including, in many cases, extensive analysis of structural connections between the data.

New in the Second Edition:

  • Chapters on crystal structures of phospholipids include new structures and more comprehensive data on bond lengths, bond angles, and torsion angles—and all coordinates are Cartesian
  • Wide-angle data is indexed whenever possible to characterize chain-packing modes in gel and crystalline lamellar phases
  • Low-angle data are analyzed in terms of the lipid and water thicknesses
  • Headgroup separations in electron density profiles for phospholipids are included, and a separate section is devoted to the in-depth analysis of electron density profiles that provides the most detailed structural information on fluid lamellar phases
  • Phase diagrams of phospholipid mixtures are vastly expanded and have been redrawn in standardized format to aid intercomparison. Cholesterol, including ternary systems, is now featured.
  • New sections on titration calorimetry, and much extended data on the temperature dependence of transfer rates
  • The greatly expanded chapter on bilayer–bilayer interactions features new and detailed information on the components of interbilayer pressures

Table of Contents

INTRODUCTION
Lipid Classification
Nomenclature of Lipids
Fatty Acids

PHOSPHOLIPIDS
Phospholipid Classification and Molecular Weights
Fatty Acid Composition of Naturally Occurring Phospholipids and of Membrane Lipids from the Yeast Lipidome
Physicochemical Properties of Phospholipids
Phospholipid pKas
Crystal Structures of Phospholipids
Phase Behavior and Hydration
Calorimetric Data
X-Ray Diffraction Data
Densitometric Data
Elastic Constants
Dynamic Properties
Phase Transition Temperatures
Phase Diagrams: Binary and Ternary Mixtures
Non-Lamellar Phases (Hexagonal and Cubic)
Critical Micelle Concentrations and Lipid Transfer
Bilayer-Bilayer Interactions
Ion-Binding Constants

GLYCOLIPIDS

Glycolipid Classification and Molecular Weights
Fatty Acid Composition of Naturally Occurring Glycolipids
Physicochemical Properties of Glycolipids
Glycolipid pKas
Crystal Structures
Phase Behavior and Hydration
Calorimetric Data
X-Ray Diffraction Data
Densitometric Data
Elastic Constants
Dynamic Properties
Phase Transition Temperatures
Phase Diagrams: Binary Mixtures
Non-Lamellar Phases (Hexagonal and Cubic)
Critical Micelle Concentrations and Lipid Transfer
Bilayer-Bilayer Interactions
Ion-Binding Constants.

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