4th Edition

Endocrine and Metabolic Disorders Clinical Lab Testing Manual, Fourth Edition

    640 Pages 40 B/W Illustrations
    by CRC Press

    Bottom Line Information to Effectively Diagnose Disorders

    The diagnosis, management, and clinical testing associated with old, traditional, and new endocrine disorders have seen numerous advances during the past 10 years since the publication of the previous edition of this bestselling resource. Updating its classic predecessor in content and format, Endocrine and Metabolic Testing Manual, Fourth Edition provides an authoritative and comprehensive resource on the clinical, diagnostic, and laboratory testing for endocrine disorders.

    Presents Relevant ICD-9 Codes for All Procedures and Tests

    Written by two widely respected authorities with more than 60 years of combined experience in diagnostic endocrinology, this medical guide is organized by endocrine organ system into 12 chapters. All tests within each chapter provide accurate, brief, but adequate, information regarding indications for the test, the procedure for performing the test, instructions for how to interpret test results, suggestions for further reading, and useful ICD-9 diagnosis codes. The book is laden with tables, making the information easy to find and use.

    Enhanced Features of the Fourth Edition:

    • Expanded Coverage: Includes most endocrine and metabolic disorders and the appropriate testing associated with their diagnoses
    • Improved Organization: Uses a more standardized format for easier use
    • Sample Calculations: Assists in calculating complex formulas with ease and accuracy
    • Highly Informative Tables: Summarizes critical information in a reader-friendly format

    With detailed instruction on how to perform and interpret clinical test procedures, this practical reference is an essential resource for endocrinologists and pathologists. Newly designed and reformatted, the new edition enables quick access to complete and authoritative information about the diagnosis, screening, and management of traditional and emerging endocrine disorders.

    Thyroid Gland Testing

    Thyroid Hormone Reserve

    Thyroid Hormone Excess

    Thyroid Malignancies

    Pituitary Gland Testing

    Corticotroph (Adrenocorticotropic Hormone) Reserve

    Corticotroph (Adrenocorticotropic Hormone) Excess

    Somatotroph (Growth Hormone) Reserve 65

    Somatotroph (Growth Hormone) Excess

    Gonadotroph Reserve

    Gonadotroph Excess

    Thyrotropin (Thyroid-Stimulating Hormone) Reserve

    Thyrotropin (Thyroid-Stimulating Hormone) Excess

    Prolactotroph (Prolactin) Reserve

    Prolactotroph (Prolactin) Excess

    Posterior Pituitary Arginine Vasopressin Reserve

    Posterior Pituitary (Arginine Vasopressin) Excess

    Detection of the Leakage of Cerebrospinal Fluid (CSF)

    in Pituitary Disease or after Transsphenoidal Surgery

    Pancreas Gland Testing (Hypoglycemia and Diabetes)

    Tests for Nonfasting or Random Hypoglycemia and Fasting Hypoglycemia

    Tests for Fasting Hypoglycemia in Adult Patients

    Tests for Hypoglycemia in Pediatric Patients

    Insulin Reserve

    Diabetes Mellitus: Diagnosis and Control of Hyperglycemia

    Criteria for Identification of Insulin Resistance or Early Diabetes Mellitus

    Risk Assessment for Complications of Diabetes Mellitus

    Nonlipid Markers of Cardiovascular Disease

    Lipid Markers of Cardiovascular Disease

    Apolipoprotein (ApoB, ApoC, ApoE, and Lp(a)) Testing

    in Disorders of Lipid Metabolism

    Tests for Complications of Hyperglycemia

    Retinopathy of Diabetes Mellitus

    Nephropathy of Diabetes Mellitus (DM)

    Neuropathy of Diabetes Mellitus

    Ketoacidopathy of Diabetes Mellitus

    Hepatopathy as a Complication of Diabetes Mellitus

    Adrenal Gland

    Glucocorticoid Reserve

    Glucocorticoid Excess in Cushing’s Syndrome

    Determining the Etiology of Cushing’s Syndrome

    Mineralocorticoid Reserve

    Mineralocorticoid Excess

    Catecholamine Excess (Pheochromocytoma)

    Virilizing Gonadal Steroids of Adrenal Origin in Females

    Bone and Parathyroid Glands

    Assessment of the Axial Skeleton (Spine and Hip)

    Bone Turnover Assessment

    Calcium Metabolism Assessment

    Parathyroid Adenoma Localization

    Discriminating Between Osteoporosis and Osteomalacia

    Male Reproductive Organ and Sexual Differentiation Testing

    Testes

    Male Infertility

    Neoplasms of the Male Reproductive Tract

    Sex Differentiation

    Female Reproductive Organ Testing

    Ovaries, Uterus, and Placenta 397

    Female Infertility, the Menopause Transition, and the Polycystic Ovary Syndrome

    Pregnancy

    Female Androgens

    Neoplasms of the Female Reproductive Tract

    Gastroenteropancreatic (Noninsulinoma) Endocrine Tumors and Endocrine Tissue Tumor Markers

    Gastrinomas

    Carcinoid Tumors

    Other Hormone-Producing Gastrointestinal Tumors

    Gastroenteropancreatic Tumor Imaging

    Tumor Markers Secreted from Endocrine Tissue

    Tests for Nutritional Status

    Body Composition Analysis and Nutritional Assessment

    Nutritional Status as Marked by Levels of Vitamins,

    Minerals, and Other Nutrients

    Diagnosis of Eating Disorders and Nutrition-Related Diseases

    Emerging or Historical Endocrine and Metabolic Tests with Potential Clinical Utility

    Tests for Thyroid Disorders

    Tests for Pituitary Tumors

    Tests for Hypoglycemia and Hyperglycemia

    Tests for Markers of Cardiovascular Disease in Diabetes Mellitus Patients

    Tests for Hyperglycemic Complications of Diabetes Mellitus

    Tests for Determining Adrenal Status

    Test for Bone Density in the Peripheral Skeleton

    Male Reproductive System Test

    Female Reproductive System Tests

    Endocrine Tumor Test

    Appendix 1: Questionnaires

    Appendix 2: Specimen Collection Protocols

    SCP-1: Urine Sample Collection: Patient Instructions

    SCP-2: Saliva Sample Collection: Patient Instructions

    SCP-3: Semen Sample Collection: Patient Instructions

    SCP-4: Blood Sample Collection Protocol: Growth Hormone (GH) Testing

    SCP-5: Blood Sample Collection Protocol: Bilateral Inferior Petrosal Sinus Sampling

    SCP-6: Blood Sample Collection Protocol: Measurement

    of Potassium [K+] in Nonhemolyzed Blood

    SCP-7: Blood Sample Collection Protocol and Report Form: Adrenal Vein Sampling

    SCP-8: Blood Sample Collection Protocol: Selective Venous Sampling

    for Localization of Hyperfunctioning Parathyroid Glands

    SCP-9: Blood Sample Collection Protocol: Measurement of Testosterone in Blood

    Biography

    Dr. Robert F. Dons, Endocrinology Nuclear Medicine Associates, San Antonio, Texas, USA

    Dr. Frank H. Wians, Jr., University of Texas, Southwestern Medical Center, Dallas, USA

    "Uniformly and remarkable scholarly for a two author treatise of this magnitude there are no weak sections or entries . . . This book should be on the reference shelves of every endocrinologist who uses clinical laboratory services . . . Overall Grading: Outstanding." – Lynn R. Witherspoon, Department of Radiology, Section of Nuclear Medicine and System Vice President and Chief Medical Information Officer, Ochsner Medical System, in LABMEDICINE, September 2009, Vol. 40, No. 9

    "A compendium of laboratory tests used in the diagnosis of endocrine and metabolic disorders in childhood and adult age. Provides much general information for practitioners…."
    —Zvi Laron, in Pediatric Endocrinology Reviews, Volume 7, No. 2, December 2009