The Chemical Components of Tobacco and Tobacco Smoke
Purchasing Options
Features
- Reviews every chemical class of components found in tobacco and tobacco smoke
- Catalogs and alphabetically indexes over 8400 tobacco and tobacco smoke components
- Presents more than 6000 cited references that deal with many topics pertinent to the components in question
- Lists the corresponding Chemical Abstracts Registry Number for most cataloged components
- Examines adverse health-related problems assigned to specific components and the smoke components reported to negate such harmful effects
- Includes a CD-ROM with a searchable, 300-page alphabetical component index
Summary
The Chemical Components of Tobacco and Tobacco Smoke chronicles the extraordinary progress made by scientists in the field of tobacco science, from its beginnings in the early 1800s to the present. This comprehensive text provides over 6000 references on more than 8400 components identified in tobacco and tobacco smoke.
Authored by two longtime researchers in tobacco science, the book examines the isolation and characterization of each component. It explores developments in pertinent analytical technology and results of experimental studies on biological activity, toxicity, and tumorigenicity, including the inhibition of adverse biological activity of specific tobacco smoke component by another tobacco smoke component. The authors discuss the controversies over the extrapolation of the biological effect of a specific component administered individually by one route versus its biological effect when the component is in a highly complex mixture and is administered by a different route. They also cite studies in which cigarette design technologies were developed to control the per cigarette mainstream smoke yield of Federal Trade Commission-defined tar and one or more specific tobacco smoke components of concern.
Through numerous references, this dynamic resource elucidates both the historical background of and recent studies in tobacco and tobacco smoke research. It furthers the knowledge base of components, arming scientists and public health officials worldwide with the most current information available.
Authors Alan Rodgman and Thomas A. Perfetti have been jointly awarded the 2010 CORESTA (Cooperative Centre for Scientific Research Relative to Tobacco) Prize for their extensive work on documenting the vast literature on the chemical composition of tobacco and tobacco smoke.Table of Contents
The Hydrocarbons
The Alkanes
The Alkenes and Alkynes
The Alicyclic Hydrocarbons
The Monocyclic Aromatic Hydrocarbons
The Polycyclic Aromatic Hydrocarbons
Alcohols and Phytosterols
Alcohols
Phytosterols
Aldehydes and Ketones
The Assertion of Aldehydes and Ketones as Ciliastatic Tobacco Smoke Components
Ciliastasis Studies with Cigarette Smoke Condensate Fractions
Ciliastasis Studies with Individual Cigarette Mainstream Smoke Components
Nose Inhalation of Environmental Tobacco Smoke vs. Mouth Inhalation of Mainstream Smoke
Carboxylic Acids
The Carboxylic Acids
The Amino Acids and Related Compounds
The Esters
The Lactones
Anhydrides
Carbohydrates and Their Derivatives
Phenols and Quinones
Phenols
Quinones
The Ethers
Nitriles
Acyclic Amines
Amides
Imides
N-Nitrosamines
Volatile N-Nitrosamines
Nonvolatile N-Nitrosamines
Tobacco-Specific N-Nitrosamines
N-Nitrosamino Acids
Tobacco-Specific N-Nitrosamines: An Exception among the Major MSS Toxicants
Direct Transfer of TSNAs from Tobacco vs. Their Formation during the Smoking Process
Infrequently Studied Tobacco and/or Smoke Secondary Amines and Their N-Nitrosamines
Flue-Curing and Tobacco-Specific N-Nitrosamines
Nitroalkanes, Nitroarenes, and Nitrophenols
Nitrogen Heterocyclic Components
Monocyclic Five-Membered N-Containing Ring Compounds
Monocyclic Six-Membered N-Containing Ring Compounds
Lactams
Oxazoles and Oxazines
Aza-Arenes
N-Heterocyclic Amines
Miscellaneous Components
Sulfur-Containing Components
Halogenated Components
Fixed and Variable Gases
Metallic and Nonmetallic Elements, Isotopes, Ions, and Salts
Elements, Isotopes, and Ions in Plants
Methods for the Detection and Identification of Metals, Ions, and Isotopes in Tobacco and Tobacco Smoke
The Transference of Elements, Isotopes, and Ions from Tobacco to Tobacco Smoke
Pesticides and Growth Regulators
Synthetic Pesticides and Plant Growth Regulator Residues on Tobacco
Naturally Occurring Plant Growth Regulators and Pesticides in Tobacco
Transfer Rates of Pesticides and Plant Growth Regulators to Mainstream Smoke
Decomposition Products of Agrochemicals in Mainstream Smoke
Methods for Analysis of Pesticides and Plant Growth Regulators
Residues of Synthetic Pesticides and Plant Growth Regulators Identified in Tobacco and Tobacco Smoke
Genes, Nucleotides, and Enzymes
Tobacco Genetics
Genes, Nucleotides, and Enzymes Identified in Tobacco
"Hoffmann Analytes"
Tobacco and/or Tobacco Smoke Components Used as Tobacco Ingredients
Pyrolysis
Individual Tobacco Types
Extracts from Tobacco
Individual Tobacco Components
Tobacco Additives
Cigarette Construction Materials (Paper, Adhesives, etc.)
Flavoring Ingredients
Carcinogens, Tumorigens, and Mutagens vs. Inhibitors, Anticarcinogens, and Antimutagens
Carcinogens, Tumorigens, and Mutagens
Anticarcinogens, Inhibitors, and Antimutagens
Alternate Exposures
Free Radicals
Introduction
Analytical Methods for Determination of Free Radicals
Free Radicals in Tobacco Smoke
Historical Review of Free Radical Research on Cigarette Smoke
Proposed Mechanisms for the Generation of Free Radicals in Mainstream Smoke
Summary
Bibliography
Index
Editorial Reviews
… the real value of the book will turn out in its daily use and it has all chances to become the standard reference book (perhaps 'The Bible') of all tobacco scientists.
— Dr. Gerhard Scherer, Editor of Beitrage zur Tabakforschung International, Bonn, Germany
I highly recommend this book as an indispensable reference source for tobacco and smoke chemists as well as other scientists involved in the study of tobacco and its products. The compilation of proper chemical names, common names, Chemical Abstract Service numbers (CAS No.), and structures alone are worth the purchase price.
—Charles R. Green, Ph.D., Retired Senior Principal Scientist, R. J. Reynolds Tobacco Company, Winston-Salem, North Carolina
Many congratulations on this monumental piece of work.
—Dr. Chuan Liu, Senior Scientist, Applied Research, Group Research & Development, British American Tobacco, Southampton, United Kingdom
As a statistician I would like to forecast: There will not be any other comprehensive work in the next 30-50 years about this topic – Rodgman – Perfetti will be the definitive book.
—Prof. Dr. Wolf-Dieter Heller, Karlsruhe, Germany
as a reference text on a laboratory shelf it will prove essential and take its place alongside the other CRC publications.
—M. Cooke, Chromatographia 2010, 71
