Handbook of Nanophysics

Handbook of Nanophysics: Nanomedicine and Nanorobotics

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Features

  • Covers actual and emerging applications in nanomedicine and nanorobotics
  • Includes introductions in each chapter—useful to nonspecialists and students
  • Enriches state-of-the-art scientific content with fundamental equations and illustrations, some in color
  • Contains chapters extensively peer reviewed by senior scientists in nanophysics and related areas of nanoscience
  • Promotes new ideas for future fundamental research

Summary

The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nanotechnology to molecular and biological processes, medical imaging, targeted drug delivery, and cancer treatment. Each peer-reviewed chapter contains a broad-based introduction and enhances understanding of the state-of-the-art scientific content through fundamental equations and illustrations, some in color.

This volume shows how the materials, tools, and techniques of nanotechnology, such as enzymatic nanolithography, biomimetic approaches, and force spectroscopy, are currently used in biological applications, including living cell biochips, biosensors, protein recognition, and the analysis of biomolecules. Drawing on emerging toxicology research, it examines the impact and risks of nanomaterials on human health and the environment. Researchers at the forefront of the field cover tissue engineering, diagnostic, drug delivery, and therapeutic applications, including organs derived from nanomaterials, quantum dots and magnetic nanoparticles for imaging, pharmaceutical nanocarriers, targeted magnetic particles and biodegradable nanoparticles for drug delivery, and cancer treatment using gold nanoparticles. They also explain how cells and skin respond to these nanomaterials.

In addition, the book investigates the next generation of nanotechnology research that is focused on nanorobotics and its potential in detecting and destroying cancer cells and detecting and measuring toxic chemicals. It considers the roles nanoheaters, nanomotors, and nanobatteries can play in this new technology.

Nanophysics brings together multiple disciplines to determine the structural, electronic, optical, and thermal behavior of nanomaterials; electrical and thermal conductivity; the forces between nanoscale objects; and the transition between classical and quantum behavior. Facilitating communication across many disciplines, this landmark publication encourages scientists with disparate interests to collaborate on interdisciplinary projects and incorporate the theory and methodology of other areas into their work.

Table of Contents

Nano-Bio Interfacing
Quantum Dots: Basics to Biological Applications, Sarwat B. Rizvi, Mo Keshtgar, and Alexander Marcus Seifalian
Viral Biology and Nanotechnology, Vaibhav Saini and Maaike Everts
Nano-Bio Interfacing with Living Cell Biochips, Yosi Shacham-Diamand, Ronen Almog, Ramiz Daniel, Arthur Rabner, and Rachela Popovtzer
Micro- and Nanomechanical Biosensors, Maria Arroyo-Hernandez, Priscila M. Kosaka, Johann Mertens, Montserrat Calleja, and Javier Tamayo
Enzymatic Nanolithography, Manfred Radmacher
Biomimetic Synthesis of Nanostructures Inspired by Biomineralization, Eike Brunner, Hermann Ehrlich, and Martin Kammer
Nanotubes for Biotechnology, Jonathan C.G. Jeynes, Vanesa Sanz-Beltran, Johnjoe McFadden, and S.R.P. Silva
Nanoscale Forces in Protein Recognition and Adhesion, Deborah Leckband
Force Spectroscopy on Cells, Martin Benoit
Nanoscale Magnetic Biotransport, Edward P. Furlani
Nanomechanical Sensors for Biochemistry and Medicine, Hans Peter Lang and Christoph Gerber
Analyzing Individual Biomolecules Using Nanopores, Meni Wanunu, Gautam V. Soni, and Amit Meller

Nanotoxicology
Chances and Risks of Nanotechnology, Armin Grunwald
Human and Natural Environment Effects of Nanomaterials, Birgit Gaiser, Martin J.D. Clift , Helinor J. Johnston, Matthew S.P. Boyles, and Teresa F. Fernandes
Toxicology, Diagnostics, and Therapy Functions of Nanomaterials, Stefano Bellucci
Cell Oxidative Stress: Risk of Metal Nanoparticles, Marija Poljak-Blazi, Morana Jaganjac, and Neven Zarkovic
Fullerene C60 Toxicology, Crystal Y. Usenko, Stacey L. Harper, Michael T. Simonich, and Robert L. Tanguay

Clinical Significance of Nanosystems
Pharmacological Significance of Nanoparticles, Carlos Medina and Marek W. Radomski
Organs from Nanomaterials, Maqsood Ahmed and Alexander Marcus Seifalian
Nanotechnology for Implants, Lijie Zhang and Thomas J. Webster
Nanotechnology for the Urologist, Hashim Uddin Ahmed, Lyndon Gommersall, Iqbal S. Shergill, Manit Arya, and Mark Emberton

Medical Imaging
Quantum Dots for Nanomedicine. Sarah H. Radwan and Hassan M.E. Azzazy
Relaxivity of Nanoparticles for Magnetic Resonance Imaging, Gustav J. Strijkers and Klaas Nicolay
Nanoparticle Contrast Agents for Medical Imaging, David P. Cormode, Willem J.M. Mulder, and Zahi A. Fayad
Optical Nanosensors for Medicine and Health Effect Studies, Tuan Vo-Dinh and Yan Zhang

Drug Delivery
Multifunctional Pharmaceutical Nanocarriers, Vladimir P. Torchilin
Nanotechnology and Drug Delivery, Fahima Dilnawaz, Sarbari Acharya, Ranjita Misra, Abhalaxmi Singh, and Sanjeeb Kumar Sahoo
Targeting Magnetic Particles for Drug Delivery, Javed Ally and Alidad Amirfazli
Biodegradable Nanoparticles for Drug Delivery, Jason Park and Tarek M. Fahmy

Response to Nanomaterials
Uptake of Carbon-Based Nanoparticles by Mammalian Cells and Plants, Pu-Chun Ke, Sijie Lin, Jason Reppert, Apparao M. Rao, and Hong Luo
Penetration of Metallic Nanomaterials in Skin, Biancamaria Baroli
Nanoparticulate Systems and the Dermal Barrier, Frank Stracke and Marc Schneider
Cellular Response to Continuous Nanostructures, Kevin J. Chalut, Karina Kulangara, and Kam W. Leong

Cancer Therapy
Nanotechnology for Targeting Cancer, Venkataramanan Soundararajan and Ram Sasisekharan
Cancer Nanotechnology: Targeting Tumors with Nanoparticles, Erem Bilensoy
Gold Nanoparticles for Plasmonic Photothermal Cancer Therapy, Xiaohua Huang, Ivan H. El-Sayed, and Mostafa A. El-Sayed
Fullerenes in Photodynamic Therapy of Cancer, Pawel Mroz, Ying-Ying Huang, Tim Wharton, and Michael R. Hamblin

Quantum Engines and Nanomotors
Energy Transport and Heat Production in Quantum Engines, Liliana Arrachea and Michael Moskalets
Artificial Chemically Powered Nanomotors, Yu-Guo Tao and Raymond Kapral
Nanobatteries, Dale Teeters and Paige L. Johnson
Nanoheaters, Christian Falconi

Nanorobotics
Atomic-Force-Microscopy-Based Nanomanipulation Systems, Cagdas D. Onal, Onur Ozcan, and Metin Sitti
Nanomanipulation and Nanorobotics with the Atomic Force Microscope, Robert W. Stark
Nanorobotic Manipulation, Lixin Dong and Bradley J. Nelson
MRI-Guided Nanorobotic Systems for Drug Delivery, Panagiotis Vartholomeos, Matthieu Fruchard, Antoine Ferreira, and Constantinos Mavroidis
Medical Micro- and Nanorobots, Sylvain Martel
Nanohandling Robot Cells, Sergej Fatikow, Thomas Wich, Christian Dahmen, Daniel Jasper, Christian Stolle, Volkmar Eichhorn, Saskia Hagemann, and Michael Weigel-Jech

Index

Editor Bio(s)

Klaus D. Sattler is a professor of physics at the University of Hawaii-Manoa in Honolulu. A pioneer in nanophysics, Dr. Sattler built the first atomic cluster source in 1980, which became a cornerstone for nanoscience and nanotechnology. In 1994, his research group at the University of Hawaii produced the first carbon nanocones. His current research focuses on novel nanomaterials, tunneling spectroscopy of quantum dots, and solar photocatalysis with nanoparticles for the purification of water. Dr. Sattler has been a recipient of the Walter Schottky Prize from the German Physical Society

 
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