Pathology of the Developing Mouse: A Systematic Approach
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Features
- Provides a single source of detailed information regarding normal data for developing mice
- Presents detailed methods for performing an effective anatomic evaluation of developing mice
- Defines a strategy for successfully investigating enbryolethal and neonatal-lethal phenotypes
- Includes an annotated list of additional resources that can guide researchers toward further study regarding in their analysis
Summary
A concise treatment of abnormal development, this book includes basic biological data concerning mouse reproduction and development, both before and early after birth. It includes guidelines for performing pathology examinations, emphasizing engineered lines but also including spontaneous mutations and toxicant-induced defects. The book also contains selected examples of abnormal anatomic development, and a detailed bibliography of additional books and internet resources. These features make it an all purpose resource on normal data for developing mice.
Table of Contents
Basic Biology of the Developing Mouse. Prenatal Development. Postnatal Development. Pathology Techniques for Developing Mice. Design of Mouse Developmental Pathology Assays. Necropsy of Developing Mice. Histologic Processing of Developing Mice. Ancillary Pathology Methods. Practical Aspects of Mouse Developmental Pathology. Pathology Evaluation of Developing Mice. Interpretation of Developmental Pathology Findings in Mice. Resources for Developmental Pathologists. Educating Mouse Developmental Pathologists.
