Emerging Protein Biotherapeutics

Iqbal S. Grewal

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June 26, 2009 by CRC Press
Reference - 368 Pages - 39 B/W Illustrations
ISBN 9781420063202 - CAT# 63200

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Features

    • Provides a comprehensive overview of protein biologics and their development for clinical applications
    • Covers the major areas currently targeted in solid tumors, hematological malignancies and autoimmune diseases
    • Includes contributions from leading international authorities
    • Includes a vivid color insert with detailed illustrations to bolster understanding

    Summary

    A Readily Applicable Framework for Novel Drug Design

    It is only 20 years since the reach of genetic knowledge has allowed for the development of protein biotherapeutics, but in that time the pace has been fast. While the literature abounds, the field has lacked a comprehensive accounting of this progress. Emerging Protein Biotherapeutics consolidates current knowledge of key protein targets important in autoimmunity and cancers, exploring basic aspects and diverse clinical application.

    Presents Strategies to Exploit Therapeutic Uses

    In this volume, leading researchers cover many aspects of biology related to protein targets, ranging from the in vivo role in the disease process, to various strategies exploiting development of these targets for therapeutic use. Each chapter includes background, a discussion of clinical implications, an account of preclinical and clinical testing of various candidates, and a listing of key references.

    This volume makes the study of protein biotherapeutics accessible at all levels of expertise. It offers an efficient and rational way to grasp the theoretical and experimental knowledge currently available while also providing a deeper understanding of disease processes. Most importantly, it presents a framework that can be readily employed by those looking to develop their own strategies in pursuit of new clinical applications.