A First Course in the Design of Experiments: A Linear Models Approach

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ISBN 9780849396717
Cat# 9671
 

Features

  • Offers a balanced treatment of theory, methods and applications using the linear model as the integrating theme
  • Emphasizes both design selection and data analysis
  • Presents analysis procedures for various designs integrated to enable easy extension to nonstandard problems
  • Includes numerous examples and exercises incorporating the use of SAS software
  • Summary

    Most texts on experimental design fall into one of two distinct categories. There are theoretical works with few applications and minimal discussion on design, and there are methods books with limited or no discussion of the underlying theory. Furthermore, most of these tend to either treat the analysis of each design separately with little attempt to unify procedures, or they will integrate the analysis for the designs into one general technique.

    A First Course in the Design of Experiments: A Linear Models Approach stands apart. It presents theory and methods, emphasizes both the design selection for an experiment and the analysis of data, and integrates the analysis for the various designs with the general theory for linear models.

    The authors begin with a general introduction then lead students through the theoretical results, the various design models, and the analytical concepts that will enable them to analyze virtually any design. Rife with examples and exercises, the text also encourages using computers to analyze data. The authors use the SAS software package throughout the book, but also demonstrate how any regression program can be used for analysis.

    With its balanced presentation of theory, methods, and applications and its highly readable style, A First Course in the Design of Experiments proves ideal as a text for a beginning graduate or upper-level undergraduate course in the design and analysis of experiments.

    Table of Contents

    INTRODUCTION TO THE DESIGN OF EXPERIMENTS
    Designing Experiments
    Types of Designs
    Topics in Text
    LINEAR MODELS
    Definition of a Linear Model
    Simple Linear Regression
    Least Squares Criterion
    Multiple Regression
    Polynomial Regression
    One-Way Classification
    LEAST SQUARES ESTIMATION AND NORMAL EQUATIONS
    Least Squares Estimation
    Solutions to Normal Equations-Generalized Inverse Approach
    Invariance Properties and Error Sum of Squares
    Solutions to Normal Equations-Side Conditions Approach
    LINEAR MODEL DISTRIBUTION THEORY
    Usual Linear Model Assumptions
    Moments of Response and Solutions Vector
    Estimable Functions
    Gauss-Markoff Theorem
    The Multivariate Normal Distribution
    The Normal Linear Model
    DISTRIBUTION THEORY FOR STATISTICAL INFERENCE
    Distribution of Quadratic Forms
    Independence of Quadratic Forms
    Interval Estimation for Estimable Functions
    Testing Hypotheses
    INFERENCE FOR MULTIPLE REGRESSION MODELS
    The Multiple Regression Model Revisited
    Computer-Aided Inference in Regression
    Regression Analysis of Variance
    SS( ) Notation and Adjusted Sums of Squares
    Orthogonal Polynomials
    Response Analysis Using Orthogonal Polynomials
    THE COMPLETELY RANDOMIZED DESIGN
    Experimental Design Nomenclature
    Completely Randomized Design
    Least Squares Results
    Analysis of Variance and F-Test
    Confidence Intervals and Tests
    Reparametrization for a Completely Randomized Design
    Expected Mean Squares, Restricted Model
    Design Considerations
    Checking Assumptions
    Summary Example-A Balanced CRD Illustration
    PLANNED COMPARISONS
    Introduction
    Method of Orthogonal Treatment Contrasts
    Nature of Response for Quantitative Factors
    Error Levels and Bonferroni Procedure
    MULTIPLE COMPARISONS
    Introduction
    Bonferroni and Fisher's LSD Procedures
    Tukey Multiple Comparison Procedure
    Scheffé Multiple Comparison Procedures
    Stepwise Multiple Comparison Procedures
    Computer Usage for Multiple Comparisons
    Comparison of Procedures, Recommendations
    RANDOMIZED COMPLETE BLOCK DESIGN
    Blocking
    Randomized Compete Block Design
    Least Squares Results
    Analysis of Variance and F-Tests
    Inference for Treatment Contrasts
    Reparametrization of a RCBD
    Expected Mean Squares, Restricted RCBD Model
    Design Considerations
    Summary Example
    INCOMPLETE BLOCK DESIGNS
    Incomplete Blocks
    Analysis for Incomplete Blocks-Linear Models Approach
    Analysis for Incomplete Blocks-Reparametrized Approach
    Balanced Incomplete Block Design
    LATIN SQUARE DESIGNS
    Latin Squares
    Least Squares Results
    Inferences for a LSD
    Reparametrization of a LSD
    Expected Mean Squares, Restricted LSD Model
    Design Considerations
    FACTORIAL EXPERIMENTS WITH TWO FACTORS
    Introduction
    Model for Two-Factor Factorial, Interaction
    Least Squares Results
    Inferences for Two-Factor Factorials
    Reparametrized Model
    Expected Mean Squares
    Special Cases for Factorials
    Assumptions, Design Considerations
    OTHER FACTORIAL EXPERIMENTS
    Factorial Experiments with Three or More Factors
    Factorial Experiments with Other Designs
    Special Factorial Experiments-2k
    Quantitative Factors, 3k Factorial
    Fractional Factorials, Confounded
    ANALYSIS OF COVARIANCE
    Introduction
    Inferences for a Simple Covariance Model
    Testing for Equal Slopes
    Multiple Comparisons, Adjusted Means
    Other Covariance Models
    Design Considerations
    RANDOM AND MIXED MODELS
    Random Effects
    Mixed Effects Models
    Introduction to Nested Designs-Fixed Case
    Nested Designs-Mixed Model
    Expected Mean Squares Algorithm
    Factorial Experiments-Mixed Model
    Pseudo F-Tests
    Variance Components
    NESTED DESIGNS AND ASSOCIATED TOPICS
    Higher Order Nested Designs
    Designs with Nested and Crossed Factors
    Subsampling
    Repeated Measures Designs
    OTHER DESIGNS AND TOPICS
    Split Plot Designs
    Crossover Designs
    Response Surfaces
    Selecting a Design
    Appendix A: Matrix Algebra
    Appendix B: Tables
    References
    Index
    Each chapter also includes exercises

    Editorial Reviews

    "I do like the blend of theory and methods found in the book and I would use it as a textbook for a first course on the design and analysis of experiments."
    -C. Brien, School of Mathematics, University of South Australia, Biometrics, December 2000

    "…it is novel in combining the theory underlying the analysis of designed experiments with a description of the methods of designing and analyzing them. The theoretical development is deeper than many design and analysis textbooks."
    Biometrics, Vol. 56, No. 4, December 2000




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