Neurogenic Inflammation

Neurogenic Inflammation

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ISBN 9780849376467
Cat# 7646
 

Features

  • Covers all the important aspects of neurogenic inflammation in health and disease
  • Considers in detail all the clinical and therapeutic aspects of neurogenic inflammatory processes in diverse clinical conditions
  • Tackles the issues surrounding the new non-peptide tachykinin antagonists
  • Examines the molecular aspects of sensory neuropeptides, particularly the recently cloned and engineered tachykinin receptors
  • Contains chapters written by recognized authorities in their fields
  • Summary

    Take advantage of this unique book - the first single-volume resource to explore all important aspects of neurogenic inflammation. An unrivaled compilation of up-to-date information, Neurogenic Inflammation contains chapters written by recognized authorities in their areas of expertise. It covers the basic mechanisms and the pathophysiological implications of neurogenic inflammatory processes and points to novel therapeutic strategies in the field of inflammatory and related diseases.
    The book highlights the many systems and mechanisms involved in neurogenic inflammation, including vasodilatation, plasma extravasation, leukocyte adhesion, smooth muscle contraction, exocrine gland secretion, and recruitment of inflammatory cells. The authors discuss the contribution of neurogenic inflammation to human diseases, such as migraine, asthma, arthritis, and inflammatory bowel disease, linked to the ubiquitous distribution of sensory nerves to organs and tissues at both the somatic and visceral level. Neurogenic Inflammation is the clear choice for a one-step, authoritative guide to the latest developments in this dynamic field.

    Table of Contents

    Molecular Biology of Tachykinins, T.M. Fong
    Post-Transcriptional Regulation of Calcitonin Gene-Related Peptide (CGRP) mRNA Production, R.B. Emeson
    Pharmacology
    Neurogenic Inflammation: Reevaluation of Axon Reflex Theory, J. Szolcsanyi
    The Vanilloid Receptor, A. Szallasi
    The Ionic Basis of Capsaicin-Evoked Responses, S. Bevan and R.J. Docherty
    Afferent Responses of Sensory Neurons, A. Dray
    Pharmacology of the Efferent Function of Primary Sensory Neurons, C.A. Maggi
    Pharmacology of Tachykinins, D. Regoli, Q.T. Nguyen, and G. Calo
    Pharmacology of Calcitonin Gene-Related Peptide, J.M. Hall and S.D. Brain
    Peptidase Modulation of Neurogenic Inflammation, J.A. Nadel
    Pathophysiology
    Sensory Neuropeptides in the Eye, R. Hakanson and Z.-Y. Wang
    Sensory Neurons in the Stomach, P. Holzer
    Sensory Neuropeptides in the Intestine, P. Holzer and L. Bartho
    Sensory Neuropeptides and Airway Diseases, P.J. Barnes
    Sensory Neuropeptides in Migraine, M.A. Moskowitz, W.S. Lee, and F.M. Cutrer
    Sensory Neuropeptides in the Lower Urinary Tract, A. Lecci and C.A. Maggi
    Sensory Neuropeptides in Arthritis, W.R. Ferrell and F.Y. Lam
    Sensory Neuropeptides in the Skin, S.D. Brain
    Interaction of the Afferent and Endocrine System, R. Amann
    Sensory Neuropeptides: Mitogenic and Trophic Functions, M. Ziche
    Clinical Studies
    Hyperalgesia and Neurovascular Reactions Following Capsaicin Application to Human Skin, J. Serra and J.L. Ochoa
    Clinical Studies on the Airway Effects of Sensory Neuropeptides, G.F. Joos
    Capsaicin as a Drug, P. Geppetti
    Non-Peptide NK-1 Antagonists: From Discovery to the Clinic, J.A. Lowe, III, R.M. Snider, and D.B. MacLean

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