Animal Lectins: A Functional View

Gerardo R. Vasta PhD, Hafiz Ahmed PhD

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October 9, 2008 by CRC Press
Reference - 596 Pages - 129 B/W Illustrations
ISBN 9780849372698 - CAT# 7269

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Features

  • Discusses lectin-mediated cell adhesion and cell surface lattice formation
  • Examines lectins that participate in glycoprotein folding, sorting and secretion, targeting, degradation, and clearance
  • Studies lectins that are involved in cell-cell interactions, signaling, and transport
  • Contains an attached CD with more than 70 color illustrations
  • Addresses lectins that are involved in the recognition and effector functions in innate and adaptive immunity
  • Presents recently discovered lectins and lectin families
  • Includes a 16-page color insert

 

Summary

Introduces Groundbreaking Approaches for Assessing Lectin Function

Lectins and their ligands are under quite a heavy microscope due to their potential applications to pharmacology, immunology, cancer therapy, and agriculture. With growing interest in the glycobiology field, the body of research related to lectin roles has grown at an explosive rate, particularly in the past 20 years. Animal Lectins: A Functional View presents the most up-to-date analysis of these carbohydrate-binding, and potentially lifesaving, proteins in one comprehensive volume.

This standard-setting resource presents new insights into the biological roles of most animal lectins, including their function in infection prevention through innate immunity. It also discusses such lectin behaviors as:

  • Glycoprotein folding
  • Sorting and targeting
  • Cell adhesion
  • Embryogenesis
  • Cell-cell interactions and signaling

Describes the Structural Basis of Protein-Carbohydrate Interactions

Under the editorial guidance of two leading protein chemistry experts and with contributions from well-recognized field authorities, this book logically and systematically discusses both intracellular and extracellular lectin functions. It is an essential springboard for future field research and a clear and concise knowledge base that glycobiology, biochemistry, and immunology researchers cannot afford to be without.