Insect Repellents

Insect Repellents: Principles, Methods, and Uses

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ISBN 9780849371967
Cat# 7196
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ISBN 9781420006650
Cat# E7196
 

Features

  • Summarizes the variety and effectiveness of current synthetic and natural repellents
  • Includes a thorough review of recent research on newly emerging formulations
  • Discusses natural repellents including those of plant, animal, and human origin
  • Examines the safety and efficacy of repellents containing deet and the other major active ingredients in current products
  • Introduces a 3D pharmacophore model for discovering new repellents
  • Summarizes world-wide systems for regulation of repellent products
  • Provides new insights on formulation and mode of action of repellent products
  • Points the way for major advancements in development and marketing
  • Summary

    Drawing together information previously found only in articles, reviews, symposia proceedings, commercial literature, and medical entomology texts, Insect Repellents: Principles, Methods, and Uses is a one-volume source on the development, evaluation, and use of repellents. It provides a thoughtful analysis of old and new information, from the ancient history of people’s attempts to avoid bites, through the use of synthetic and botanical products, to pioneering techniques for development of repellent products. After reading this book, you will be able to perform the next step in research, thoroughly evaluate data on repellents, and choose the best products for any situation.

    The editors introduce and define the word “phagomone” to fill the gap created by the many different meanings attributed to the word “repellent.” They present the history of repellent production that has led to the formulations currently in use and discuss the biological variety of phagomones as they function in nature. The book then delineates the methods used to assess the activity of phagomones and repellent products.

    A special feature of the book is its coverage of what many consider the cutting-edge in repellent testing: automated tests of the arthropods’ responses, the use of computer models of chemistry, and the use of molecular biology methods. The book comprehensively compares active ingredients and includes an index of illustrated chemical structures that lists most chemicals involved in repellent development.

    A thought-provoking discussion of the process of testing formulated products and comprehensive reviews of natural and synthetic active ingredients round out the book’s coverage. It supplies an in-depth understanding of the variety of purposes served by repellent bioassays and lays the foundation for evaluating data and designing new tests as well as developing and delivering new tools and approaches. This book provides all the information you need to give evidence-based recommendations.

    Table of Contents

    Preface, M. Debboun, S. Frances, and D. Strickman

    Principles


    History of Insect Repellents, S.J. Moore and M. Debboun
    Terminology of Insect Repellents, G.B. White
    Vertebrate Chemical Defense: Secreted and Topically Acquired Deterrents of Arthropods, P.J. Weldon and J.F. Carroll
    Human Emanations and Related Natural Compounds that Inhibit Mosquito Host-Finding Ability, U.R. Bernier, D.L. Kline, and K.H. Posey

    Methods


    Standard Methods for Testing Mosquito Repellents, D.R. Barnard, U.R. Bernier, R.-d. Xue, and M. Debboun
    Biometrics and Behavior in Mosquito Repellent Assays, D.R. Barnard and R.-d. Xue
    Animal Models in Research and Development of Insect Repellents for Human Use, L.C. Rutledge and R.K. Gupta
    Techniques for Evaluating Insect Repellents, J.M. Govere and D.N. Durrheim
    Use of an Olfactometer for Determining Attractants and Repellents, J.F. Butler
    Discovery and Design of New Arthropod/Insect Repellents by Computer-Aided Molecular Modeling, R.K. Gupta and A.K. Bhattacharjee
    Molecular-Based Chemical Prospecting of Mosquito Attractants and Repellents, W.S. Leal

    Products and Active Ingredients


    Evaluation of Topical Insect Repellents and Factors that Affect Their Performance, S.P. Carroll
    Repellents Used in Fabric: The Experience of the U.S. Military, W.C. McCain and G.J. Leach
    Plant-Based Insect Repellents, S.J. Moore, A. Lenglet, and N. Hill
    Considerations on the Use of Botanically-Derived Repellent Products, E.J. Gerberg and R.J. Novak
    Efficacy and Safety of Repellents Containing Deet, S.P. Frances
    Lipodeet: An Improved Formulation for a Safe, Long-Lasting Repellent, B. Salafsky, T. Shibuya, Y.-X. He, J. Ha, and K. Ramaswamy
    Picaridin, S.P. Frances
    DEPA: Efficacy, Safety and Use of N,N-Diethyl Phenylacetamide, a Multi-Insect Repellent, S. Prakash, R. Vijayaraghavan, and K. Sekhar
    PMD (p-Menthane-3,8-Diol) and Quwenling, D. Strickman
    IR3535® (Ethyl Butylacetylaminopropionate), G. Puccetti
    Older Synthetic Active Ingredients and Current Additives, D. Strickman
    Area Repellent Products, D. Strickman

    Uses


    User Acceptability: Public Perceptions of Insect Repellents, S.P. Frances and M. Debboun
    Commercially Available Insect Repellents and Criteria for Their Use, R.-D. Xue, A. Ali, and J.F. Day
    Global Regulatory Perspectives on Insect Repellent Development and Registration, K.J. Sweeney
    Epilogue
    Prospects for the Future, D. Strickman, S.P. Frances, and M. Debboun
    Appendices Index

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