Inhalation Toxicology, Second Edition

Harry Salem, Sidney A. Katz

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Features

  • Focuses on the methods, measurements, and mechanisms of inhalation toxicology
  • Includes coverage of the inhalation of biological agents
  • Discusses the importance of developing chemical exposure numbers for emergency response planning purposes
  • Highlights the use of new techniques such as toxicokinetic models, genomics, and proteomics
  • Features coverage of in vivo studies and animal models, therapeutics, and chemicals
  • Examines the data, methods, models, and guidelines used in health risk assessment to determine inhalation endpoints
  • Summary

    Written by internationally recognized scientists from academic, industrial, and governmental sectors, Inhalation Toxicology, Second Edition details the methods and materials used in the theoretical and applied aspects of inhalation toxicology. The editors emphasize the relationship between the respiratory system and toxicology of inhaled substances and examine methods and measurements for improving our understanding of the basic mechanisms of effects.

    The book delineates key issues in the field such as regulatory aspects of exposure and testing, testing equipment and methods, biomarkers, pathology, allergies and immunology, irritation of the respiratory tract, and risk assessment. It covers the inhalation of bioaerosols and toxins, ranging from anthrax to household molds as well as genomics, proteomics, and low-level exposure toxicants such as tobacco smoke and chemical warfare agents. Highlights include coverage of the Acute Exposure Guidelines and Emergence Response Guidelines and recent changes in the European and American guidelines for testing procedures.

    The book focuses on key issues associated with airborne substances and provides critical reviews of the latest advances. Presenting sophisticated concepts in a readable, accessible format, the book distills the latest information into practical knowledge.

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