The IACUC Handbook, Second Edition
Features
Summary
Since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States.
By addressing questions and problems that often confront institutions, The IACUC Handbook, Second Edition provides accurate, succinct answers. It features comprehensive updates for all pertinent federal laws, regulations, and policies. It also contains an expanded survey of IACUC practices from institutions around the nation.
With accessible information, this new editionprovides a foundation for those attempting to understand and implement the many and varied responsibilities of these committees.
Table of Contents
Origins of the IACUC
Circumstances Requiring an IACUC
Creation of an IACUC
Reporting Lines of the IACUC
General Composition of the IACUC and Specific Roles of the IACUC Members
Frequency and Conduct of Regular IACUC Meetings
General Format of IACUC Protocol Forms
Submission and Maintenance of IACUC Protocols
General Concepts of Protocol Review
Amending IACUC Protocols
Continuing Review of Protocols
Justification for the Use of Animals
Justification for the Number of Animals to be Used
Animal Acquisition and Disposition
Animal Housing and Use Sites
Pain and Distress
Euthanasia
Surgery
Antigens, Antibodies, and Blood Collection
Occupational Health and Safety
Personnel Training
Academic Freedom and Proprietary Information
General Concepts of the Facility Inspection and Program Review
Inspection of Animal Housing Areas
Inspection of Individual Laboratories
Inspection of Surgery Areas
Assessment of Veterinary Care
Laboratory Animal Enrichment
Animal Mistreatment and Protocol Noncompliance
Post –Approval Monitoring
Appendix A. Animal Welfare Act
Appendix B. Animal Welfare Act Regulations
Appendix C. Health Research Extension Act of 1985
Appendix D. Public Health Service Policy on Humane Care and Use of Laboratory Animals
Appendix E. U.S. Government Principles for the Utilization and Care of Vertebrate Animals in Testing, Research, and Training
Index
Editorial Reviews
“The IACUC Handbook is an interesting interactive handbook with a unique format that introduces a complex subject of rules, policy, and guidelines for an animal care program and the committee given the task of oversight of that program and offers interpretation into those guidelines. …easy to read, complete with a multitude of reference material …useful to any new IACUC members or members of IACUC who have additional questions regarding policies and regulations concerning animal programs at their or other institutions.”
—Sandra L. Jex, DVM, ALN Magazine
“…Those who are new to IACUCs as well as seasoned committee members and administrators will find a wealth of information on the regulatory aspects that govern committee function and animal health. This book remains a valuable source of practical information on issues facing IACUCs, and I highly recommend it for the libraries of all those who are part of an IACUC or contribute to IACUC support.”
—Rebecca S. Schwiebert, D.V.M., Ph.D, C.A.C.L.A.M., American Journal of Veterinary Medicine, Vol. 69, No. 1
Praise for the First Edition
“Finally a much-needed text that deals with issues facing Institutional Animal Care and Use Committees is available. The editors and chapter contributors have provided an excellent reference book for IACUC administrators, chairpersons, and laboratory animal professionals alike. It is a long-awaited manuscript to assist with the resolution of problems that face many Institutional Animal Care and Use Committees. Its ‘question and answer’ format is very useful … an extremely well-written reference that should be included in the training of all personnel that are involved with Institutional Animal Care and Use Committees. It is a text that can be referenced for a plethora of issues that face these committees … an indispensable book in our field.”
—Ellen M. Levee, D.V.M., Laboratory Animal Practitioner
“This reasonably priced book would be a valuable addition to the library of any IACUC, aiding in semi-annual assessments of the operation and compliance of the IACUC and in training new members in their role in and the function of the IACUC.”
—David M. Moore, D.V.M., M.S., DACLAM, American Journal of Veterinary Research
