Handbook of Animal Models in Transplantation Research

Published:
December 09, 1993 by CRC Press - 368 Pages
Author(s):
Donald V. Cramer, Cedars-Sinai Medical Center, Beverly Hills, CA; Luis G. Podesta; Leonard Makowka

Purchasing Options

Hardback
$460.00
Add to cart
ISBN 9780849336294
Cat# 3629
 

Features

  • Provides a detailed description of commonly performed transplantation surgeries in experimental animals
  • Presents historical background information, anatomical descriptions, experimental applications, and complications for each model
  • Includes experimental models in rodents, rabbits, and larger experimental species, including pigs, dogs, and primates
  • Features individual chapters for the use of immunosuppressive agents; bone marrow transplantation, including graft-versus-host disease; and the appropriate selection of xenograft surgical models

    • Summary

    Handbook of Animal Models in Transplantation Research is a new surgical handbook that provides detailed information concerning the transplantation of a variety of tissues in experimental animals. The text provides a practical guide for experienced investigators to develop new surgical transplantation models for application in a laboratory setting. Each chapter gives consistent descriptions of the anatomical considerations, the surgical model, and potential applications of the procedure. The organ systems covered include the heart and/or lung, liver, small bowel, kidneys, and bone marrow. The species selected for representation of each experimental model is based upon the usefulness and frequency of the model for studies in transplantation research. This book is important for all experimental surgeons, transplantation biologists, and students of surgical research.

    Table of Contents

    Introduction (L. Makowka, D.V. Cramer, and L. Podesta). Kidney Transplantation: Renal Transplantation in the Rat (M.H. Sayegh and E.L. Milford). Renal Transplantation in the Rabbit (W. Lopatin, H. Noguchi, and L. Makowka). Kidney Transplantation in Yucatan Miniature Swine (T. Howard, C.A. Cosenza, D.V. Cramer, and L. Makowka). Liver Transplantation: Liver Transplantation in Mice (S. Qian and J.J. Fung). Orthotopic Rat Liver Transplantation (M. Knoop, R. Steffen, D.V. Cramer, and L. Makowka). Liver Transplantation in the Dog (C.E. Broelsch, L. Stevens, and J.B. Piper). Liver Transplantation in the Pig (D. Kahn and R. Hickman). Liver Transplantation in Primates (O. Imventarza, H.L.R. Rilo, A. Oks, J.J. Fung, and T.E. Starzl). Transplantation of Hepatocytes (A.A. Demetriou, J. Rozga, and A.D. Moscioni). Pancreas Transplantation: Whole Pancreas Transplantation in the Rat (M.J. Orloff and M.S. Orloff). Isolation of Pancreatic Islets for Transplantation Studies (C. Ricordi). Heart Transplantation: Heterotopic Heart Transplantation in Rodents (F.A. Chapman, D.V. Cramer, and L. Makowka). Heart, Lung, and Heart-Lung Transplantation in the Dog and the Pig (R. Saito and P. Waters). Heart Transplantation in Primates (D.K.C. Cooper, Y. Ye, and M. Niekrasz). Small Bowel and Multivisceral: Multivisceral Transplantation in the Rat (N. Murase and T.E. Starzl). Intestinal Transplantation in the Rat (D.R. Grant, R. Zhong, and R. Black). Multivisceral Transplantation in the Pig (L. Podesta, D.V. Cramer, and L. Makowka). Bone Marrow and Graft-Versus-Host Disease: Bone Marrow Transplantation and Graft-Versus-Host Disease in Mice (R. Korngold). Bone Marrow Transplantation in Dogs (H.J. Deeg and R. Storb). Bone Marrow Transplantation in the Pig (D.H. Sachs, P. Guzzetta, C.V. Smith, K. Nakajima, and A. Mixon). Xenotransplantation: The Use of Xenografts in Experimental Transplantation (D.V. Cramer and L. Makowka). Immunosuppressive Agents: The Use of Immunosuppressive Agents in Animal Models of Experimental Transplantation (C.A. Cosenza, D.V. Cramer, and L. Makowka).

    Editorial Reviews

    "This book is an excellent reference for anyone interested in transplant research...a good investment."
    -Susan Harper, SYNAPSE, 28(4), December 1995

    Related Titles