Drug Abuse Handbook

Published:
December 29, 1997 by CRC Press - 1,152 Pages
Editor(s):
Steven B. Karch, MD, FFFLM, Consultant and Cardiac Pathologist & Toxicologist, Berkeley, California, USA

Purchasing Options

Hardback
Not available
in your region
ISBN 9780849326370
Cat# 2637
 

Features

  • Step-by-step approach to the management of drug-related medical emergencies simplifies decision making
  • Flow algorithms and decision trees for postmortem toxicology eliminate dangerous mistakes and omissions
  • Sample calculations show how alcohol levels are estimated in DUI cases
  • Thousands of prescreened reference sources help you navigate the literature without wasting time
  • Appendices provide common terms and abbreviations, references to the postmortem toxicology section, sample calculations, and a list of normal heart weights
  • A user-friendly, detailed index allows for quick location of specific information

    • Summary

    This is the handbook that professionals who deal with problems related to drugs and drug abuse have been waiting for. The impressive list of more than 80 contributors, each experts and leaders in their field, testifies to the importance of this outstanding new handbook. The volume contains detailed discussions of drug-related issues in criminalistics, pathology, and toxicology. Impairment testing and the pharmacokinetics of abused drugs are examined in detail, as is the field of workplace drug testing, the use of alternate testing matrices, drugs in sports, addiction medicine, and drug-related medical emergencies.

    The handbook focuses on the most urgent drug abuse-related problems of today

  • An entire section is devoted to alcohol abuse, including a scientific appraisal of the most common drunk driving defenses, complete with sample calculations.
  • Problems of postmortem toxicology are thoroughly detailed and an appendix lists key references for the most widely used analytic methods.
  • An in-depth analysis of legal questions, including fetal rights and workplace testing
  • Examination of the principles of addiction medicine and how doctors handle substance abuse problems
  • A section addressing drug use by athletes, including a summary of current Olympic Committee Regulations regarding substance use and the latest information on detecting abuse of Human Growth Hormone and Erythropoietin

    Whether you are approaching the issue of drug abuse from a medical, psychological, toxicological, or legal perspective, the Drug Abuse Handbook is the most authoritative and complete resource available.

    • Table of Contents

    CRIMINALISTICS-INTRODUCTION TO CONTROLLED SUBSTANCES, J.P. Bono
    Definition and Scheduling of Controlled Substances
    Scheduling of Controlled Substances
    Controlled Substance Analogue Enforcement Act of 1986
    Controlled Substances
    Legitimate Pharmaceutical Preparations
    Unique Identify Factors
    Analyzing Drugs in the Forensic Science Laboratory
    Comparative Analysis
    Clandestine Laboratories
    PATHOLOGY OF DRUG ABUSE, C.V. Wetli
    Preliminary Observations, C.V. Wetli
    Techniques for Examination of the Heart, R. Virmani, A.P. Burke, and A. Farb
    Myocardial Alterations in Drug Abusers, S.B. Karch
    Endocarditis, M.D. Bell
    Vascular Effects of Substance Abuse, F.D. Kolodgie, A. Burke, J. Narula, F.G. Mullick, and R. Virmani
    Lung Disease, M.D. Bell
    Disorders of the Central Nervous System, M.D. Bell
    Miscellaneous Complications, C.V. Wetli
    PHARMACOKINETICS: DRUG ABSORPTION, DISTRIBUTION, AND ELIMINATION, A.J. Jenkins and E.J. Cone
    Basic Concepts and Models
    Pharmacokinetic Modeling
    Physiological Models
    Pharmacokinetic-Pharmacodynamic Correlations
    Toxicokinetics
    Factors Affecting Pharmacokinetic Parameters
    Pharmacokinetics of Specific Drugs
    PHARMACODYNAMICS, S.J. HEISHMAN
    Effects of Abused Drugs on Human Performance: Laboratory Assessment, S.J. Heishman
    Performance Measures of Behavioral Impairment in Applied Settings, T.H. Kelly, R.C. Taylor, S.J. Heishman, and D.J. Crouch
    Effects of Abused Drugs on Pupillary Size and the Light Reflex, W.B. Pickworth, R.V. Fant, and E.B. Bunker
    Evaluating Abuse Liability: Methods and Predictive Value, K.L. Preston and S.L. Walsh
    ALCOHOL, A.W. JONES
    Measuring Acute Alcohol Impairment, C.S. Martin
    Measuring Blood-Alcohol Concentration for Clinical and Forensic Purposes, A.W. Jones and D.J. Pounder
    Measuring Alcohol Postmortem, D.J. Pounder, and A.W. Jones
    Biochemical Tests for Acute and Chronic Alcohol Ingestion, A. Helander and A.W. Jones
    NEUROCHEMISTRY OF DRUG ABUSE, D.C. MASH AND J.K. STALEY
    The Dopamine Transporter and Addiction, J.W. Boja and W.M. Meil
    Neuropsychiatric Consequences of Chronic Cocaine Abuse, D.C. Mash
    Neurochemical Adaptations and Cocaine Dependence, J.K. Staley
    The Neurobiology of Relapse, D.W. Self
    Serotonergic Dysfunction During Cocaine Withdrawal: Implications for Cocaine-Induced Depression, M.H. Baumann and R.B. Rothman
    Neurochemistry of Psychedelic Drugs, J.C. Callaway and D.J. McKenna
    ADDICTION MEDICINE, K. WOLFF
    The Principles of Addiction Medicine, D. Raistrick
    Substitute Prescribing, K. Wolff
    Treatment of Withdrawal Syndromes, J. Banbery
    Replacement Prescribing, K. Wolff and D. Fraser
    Management of Comorbidity, D. Raistrick
    Toxicologic Issues, A.W.M. Hay
    MEDICAL COMPLICATIONS OF DRUG ABUSE, N.L. Benowitz
    Drug-Related Syndromes, N.L. Benowitz
    Emergency Management of Drug Abuse-Related Disorders, N.L. Benowitz
    SPORTS, J. SEGURA
    Introduction, J. Segura
    Specific Agents, R. de la Torre
    Anabolic Androgenic Steroids, D.H. Catlin
    Detection of Exogenous Anabolic Androgenic Steroids, W. Schänzer
    Growth Hormone Abuse in Elite Athletes, R.C. Cuneo, J.D. Wallace, and P. Sönksen
    Erythropoietin, B. Ekblom
    Summary of International Olympic Committee Regulations, J. Segura
    WORKPLACE DRUG TESTING, Y.H. CAPLAN
    Development and Scope of Regulated Testing, J.M. Walsh
    The College of American Pathologists Voluntary Laboratory Accreditation Program, J. Baenzinger
    Analytical Considerations and Approaches for Drugs, M. Peat and A.E. Davis
    Urine Specimen Suitability for Drug Testing, R.E. Winecker and B.A. Goldberger
    The Role of the Medical Review Officer, S. St. Clair
    Alternative Specimens for Drug Detection and Approaches for Non-Regulated Drug Testing, D. Crouch
    Implementation of Alcohol Testing: General Considerations and Processes, D.R. Smith
    ALTERNATIVE TESTING MATRICES, M.A. Huestis and E.J. Cone
    Factors Effecting Drug Disposition. Saliva. Sweat. Hair. Amniotic Fluid. Meconium. Breast Milk. Skin. Nails. Semen. Sebum. Cerumen. Breath. Fat. Conclusions.
    POSTMORTEM TOXICOLOGY, W.L. HEARN
    Introduction to Postmortem Toxicology, W.L. Hearn and H.C. Walls
    Specimen Selection, Collection, Preservation, and Security, B.R. Hepler and D.S. Isenschmid
    Common Methods in Postmortem Toxicology, W.L. Hearn and H.C. Walls
    Strategies for Postmortem Testing, W.L. Hearn and H.C. Walls
    Interpretation of Postmortem Drug Levels, G.R. Jones
    DRUG LAW
    Current Legal Issues of Workplace Drug Testing, T.F. Schulz
    DUI Defenses, A.W. Jones and B. Logan
    Fetal Rights, S.M. Mohaupt
    APPENDICES
    Glossary of Common Terms, H.C. Walls
    Common Abbreviations, H.C. Walls
    References for Methods of Drug Quantitative Analysis
    Sample Calculations, B.K. Logan and A.W. Jones
    Normal Heart Weights
    INDEX

    Editorial Reviews

    "A large portion of my forty years in the forensic field has been spent in drug identification. Please encourage Dr. Karch to keep up his good work as he is filling voids in most of our libraries."
    -Letter from George M. Taft, Jr., Director, Scientific Crime Detection Laboratory, Anchorage, Alaska

    "…it covers, in depth and breadth, a veritable cornucopia of relevant aspects relating to this important area of study. …Virtually no stone is left unturned. This is the most comprehensive volume I have ever had the pleasure of reading."
    - Joseph Horvat, Weber State University, Ogden, Utah, in Science Books and Films

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