Toxicology and Ecotoxicology in Chemical Safety Assessment
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Summary
The use of chemicals in any workplace in the developed world is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the handling and use of chemicals. In practice, those risk assessments are generally carried out by a range of competent people, be it the corporate safety manager, the R&D chemist or the manufacturing unit manager. This book will guide those personnel in the understanding, interpretation and application of toxicological and ecotoxicological information, supplied on a material safety data sheet, when planning the safe handling and use of chemicals.
This volume is directed at corporate health & safety officers and safety managers; R&D chemists; process chemists and engineers, and manufacturing unit managers & supervisors in the pharmaceutical industry and the bulk, fine and specialty chemicals industries.
Table of Contents
TOXICOLOGY
Introduction
Toxicity
Chemical Irritancy and Corrosive Effects
Chemical Allergies
Genetic Toxicology and Carcinogenicity
Reproductive Toxicology
The Nervous System
Alternative to Animal Testing
ECOTOXICOLOGY
Introduction
Aquatic Toxicity Testing
Chemical Persistence and Biodegradability
Bioaccumulation
CLASSIFICATION AND LABELLING OF CHEMICALS ACCORDING TO THEIR HAZARDOUS NATURE
Introduction
Europe
The Dangerous Substances Directive 67/548/EEC
Preparations
Canada
USA
Summary
HANDLING CHEMICALS IN THE WORKPLACE
Introduction
Risk Assessment
Chemical Hazards
CHEMICAL CONTROL
Introductions
Chemical Control in Europe
Chemical Control in the USA
Chemical Control in Australia
THE MATERIAL SAFETY DATA SHEET
Introduction
How to Deal with Toxicological or Ecotoxicological Data Gaps
Glossary of Terms
Index
