This unique compilation of chapters reviews a broad range of topics at the cutting edge of hearing research. The authors include many of the top auditory scientists in the world as well as some of the brightest rising stars. Although the book obviously focuses on the exciting, revolutionary work being done with mice, the authors have made a strong effort to provide general background information and present the insights gained from the study of mice in the greater context of auditory research. Each section includes specific procedures, potential problems and their solutions, and tricks of the trade gleaned from the authors. The book contains numerous figures and tables, more than 2,000 references, and much data not previously published. Handbook of Mouse Auditory Research: From Behavior to Molecular Biology provides state-of-the-art research with a clear look at what the future holds.
Audiology, Auditory Behavior and Psychophysics
Auditory Communication Among Adults, John G. Nyby
Behavioral Assessment of Hearing, Rickye S. Heffner and Henry E. Heffner
Focus: Sound -localization Acuity Changes with Age in C57BL/6J Mice, Rickye S. Heffner, Gimseong Koay, and Henry E. Heffner
Noninvasive Assessment of Auditory Function: Distortion Product Otoacoustic Emissions and Auditory Brainstem Responses, Kourosh Parham, X.-M. Sun, and D.O. Kim
The Acoustic Startle Response: Reflex Elicitation and Reflex Modification by Preliminary Stimuli, James R. Ison
Modulation of the Acoustic Startle Response by Background Sound in C57BL/6J Mice, Stephanie Carlson and James F. Willott
Focus: Learning/conditioning Associated with the Auditory System, William Falls and Paul Pistell
Peripheral Auditory System
The Outer and Middle Ear, James C. Saunders and Mark A. Crumling
The Development of the GABAergic Innervation in the Organ of Corti, Matthew Kelley and Lynne Bianchi
Cellular and Molecular Development of the Organ of Corti, Matthew Kelley and Lynne Bianchi
The Biology and Function of Neurotrophins in the Peripheral Auditory System, Hinrich Staecker, Stuart Apfel, and Thomas R. Van De Water
Preparation and Evaluation of the Temporal Bone, Barbara Bohne, Gary Harding, and Henry C. Ou
Cochlear Hair Cell Densities and Inner Ear Staining Techniques, Dalian Ding, Sandra L. McFadden, and Richard J. Salvi
Effects of an Augmented Acoustic Environment on the Mouse Auditory System, James F. Willott, Victoria Sundin, and Jennifer Jeskey
Cochlear Blood Flow, Alfred L. Nuttall
Development of the End Bulbs of Held, Charles J. Limb and David K. Ryugo
Central Auditory System
Focus: Diversity of the Mouse Central Auditory System, James F. Willott
Anatomy of the Central Auditory System, Robert D. Frisina and Joseph P. Walton
Cytoarchitectonic Atlas of the Cochlear Nucleus of the Mouse, Joseph Trettel and D. Kent Morest
Functional Circuitry of the Cochlear Nucleus: in vitro Studies in Slices, Michael J. Ferragamo and Donata Oertel
Focus: GABA and Glycine Neurotransmission in Mouse Auditory Brainstem Structures, Donald M. Caspary
Calcium Binding Proteins in the Central Auditory System: Modulation by Noise Exposure and Aging, Esma Idrizbegovic, Nenad Bogdanovic and Barbara Canlon
Auditory Neurons in the Reticular Formation of C57BL/6J Mice, Stephanie Carlson
Aging and the Central Auditory System, Robert D. Frisina and Joseph P. Walton
Focus: Elicitation and Inhibition of the Startle Reflex by Acoustic Transients: Studies of Age-related Changes in Temporal Processing, James R. Ison, Joseph P. Walton, Robert D. Frisina, and William E. O'Neill
Genetics and the Mouse Auditory System
Human Hereditary Hearing Impairment: Research Progress Fueled by the Human Genome Project and Mouse Models, James F. Battey, Jr.
Genetic Analysis of Non-Transgenic Mouse Mutations Affecting Ear Morphology or Function, Kenneth R. Johnson, Qing Yin Zheng, and Verity A. Letts
Inbred Strains of Mice for Genetics of Hearing in Mammals Searching for Genes for Hearing Loss, Lawrence C. Erway, Q.Y. Zheng and Kenneth R. Johnson
Mapping the Genes for the Acoustic Startle Response (ASR) and Prepulse Inhibition of the ASR in the BXD Recombinant Inbred Series: Effect of High Frequency Hearing Loss and Cochlear Pathology, Robert Hitzemann, James Bell, Erik Rasmussen, and James McCaughran, Jr.
Transgenic Mice: Genome Manipulation and Induced Mutations. Lina M. Mullen and Allen F. Ryan
Murine Models of Diseases or Conditions Affecting the Auditory System
Noise-induced Hearing Loss, Rickie R. Davis
The Role of Superoxide Dismutase in Age-related Hearing Loss: Clues from SOD 1 Knockout Mice, Sandra L. McFadden, Dalian Ding, Kevin Ohlemiller, and Richard J. Salvi
Mouse Models of Immunologic Diseases of the Ear, Dennis R. Trune
Focus: Muscular Dystrophy Mouse Models and Hearing Deficits, De-Ann M. Pillers, and Dennis Trune
Hypothyroidism and Hearing, Edward Walsh and JoAnn McGee
Allport's and Usher's Syndromes, JoAnn McGee and Edward Walsh
Preventing Sensory Loss in a Mouse Model of Lysomal Storage Disease, Kevin K. Ohlemiller, Carol A. Vogler, Thomas M. Daly, and Mark S. Sands
Auditory Brainstem Responses in a Mouse with Deletion of the RAB-3A Gene, Robert Burkard, Blanca Durand, Carrie Secor, and Sandra McFadden
Focus: Mutations of the BRN4/POU3F4 Locus, E. Bryan
Crenshaw III