1st Edition

DNA Arrays Technologies and Experimental Strategies

Edited By Elena V. Grigorenko Copyright 2001
    190 Pages 16 Color & 76 B/W Illustrations
    by CRC Press

    A quantum leap in technology took place a few years ago with the introduction of cDNA arrays that have been developed in response to the need for simultaneous analysis of the patterns of expression of thousands of genes. DNA Arrays: Technologies and Experimental Strategies offers a view of different aspects of this rapidly developing technology, including oligonucleotide and electrochemical arrays. Distinguished investigators from academia and industry provide up-to-date insights into methodological fundamentals of construction of DNA arrays, optimization of hybridization conditions, the use of expression data in bioinformatics, software tools, and the application of microarray technology for drug discovery.

    Introduction
    Technology Development for DNA Chips, H. Eickhoff, U. Schneider, E. Nordoff, L. Nyarsik, G. Zehetner, W. Nietfried, and G. Lehrach
    Experimental Design for Hybridization Aray Analysis of Gene Expression, W. Freeman and K. Vrana
    Nylon Platform: Pros and Cons, E. Grigorenko, S. Weber
    Oligonucleotide Array Technologies for Gene Expression Profiling, D. Doris, R. Ramakrishnan, T. Sendera, S. Magnuson, and A. Mazumder
    Electrochemical Detection of Nucleic Acids, R. Witwer, E. Espenhahn, M. Napier, and H. Thorp
    DNA Microarrays in Neurobiology, M-C. Potier, B. Golfier, N. Cauli, B. Gibelin, B. Le Bourdelles, B. Lambolez, S. Kuhlmann, P. Marc, F. Devaux, and J. Rossier
    Data Management in Microarray Fabrication, Image Processing and Data Mining, A. Kuklin, S. Shah, B. Hoff, and S. Shams
    Zeroing In on Essential Gene Expression Data, S. Fuhrman, S. Liang, X. Wen, and R. Somogyi
    Application of Arrayed Libraries for Analysis of Differential Gene Expression Followed Chronic Cannabinoid Exposure, E. Grigorenko, J. Kittler, and S. Deadwyler
    Supplier List
    List of Web Sites Related to DNA Arrays
    Index

    Biography

    Elena V. Grigorenko