Circadian Physiology, Second Edition

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$145.95
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ISBN 9780849322334
Cat# 2233
 

Features

  • Presents review summaries, suggestions for further readings, directions to pertinent web sites, and exercises  with solutions at the end of each chapter
  • Includes a CD-ROM that provides grouping of programs designed to offer practical experience in data analysis, as well as tutorials and simulation programs introduced throughout the text
  • Contains a complete Dictionary of Circadian Physiology — with information on meaning, etymology, and pronunciation — as well as a table of equivalency in eight foreign languages
  • Provides the principles in physiology, biochemistry, molecular biology, neuroscience, statistics, computer science, and philosophy of science needed to comprehend the various chapters
  • Offers elaborate guidance on how to utilize the text within the constraints of a fifteen week university course
  • Find out about the tau-mutant hamster at Dr. Refinetti’s laboratory web site at www.circadian.org. This golden hamster has a 20 instead of a 24-hour circadian cycle. Researchers and students alike are encouraged to use the site’s e-mail link to send queries on specific issues.
     

    Summary

    While the first edition of the critically acclaimed and highly popular Circadian Physiologyoffered a concise but rigorous review of basic and applied research on circadian rhythms, this newest edition provides educators with the primary textbook they need to support a course on this cutting-edge topic. Maintaining the same accessible multidisciplinary approach of the original, this volume provides a thorough grounding in a broad range of topics, while offering instructors many unique advantages. 

    This impressive handbook provides the foundation, along with the supplementary material, and all the implementation details necessary to run a cutting-edge class on an exceptionally timely and intriguing topic.

    This edition of Circadian Physiologynot only updates the material covered in the original, but it also expands its length and scope, presenting many new findings, such as the discovery of new retinal photoreceptors, the identification of several non-hypothalamic circadian pacemakers, and the elucidation of genomic and proteomic mechanisms of biological timing. Three times the length of the original, this volume includes approximately 730 figures and 5,000 bibliographic references, making it a true handbook of circadian physiology.

    Table of Contents

    Every chapter includes these sections: Summary, Exercises, Suggestions for Further Reading, Web Sites to Explore, and Literature Cited
    PART I History and Methods
    Early Research on Circadian Rhythms: Remote Past; 20th Century; Current Trends; Ethics of Animal Research.             

    Research Methods in Circadian Physiology: The Scientific Method;  Research on Populations and Organisms; Research on Organs, Cells, and Molecules; Research on the Environment.              

    Analysis of Circadian Rhythmicity: Data Analysis; Mean Level, Amplitude, and Phase; Period, Waveform, and Robustness; Statistical Significance .


    PART II Phenomenology

    Ultradian and Infradian Rhythms: Environmental Rhythms; Ultradian Rhythms; Infradian Rhythms; Annual Rhythms

    Daily and Circadian Rhythms: Environmental and Populational Rhythms; Behavioral Rhythms; Autonomic Rhythms.       


    PART III Mechanisms

    Endogenous Mechanisms: Endogenous Rhythmicity; Inheritance Mechanisms; Single or Multiple Oscillators.                                               

    Photic Environmental Mechanisms: Nonparametric Theory of Entrainment; Photic Parameters; Synthesis and Models.      

    Nonphotic Environmental Mechanisms: Nonphotic Entrainment; A Separate Food-Entrainable Pacemaker.                                        

    Integration of Mechanisms: Internal Order; Ecology and Evolution; Lifetime Changes.         

    Homeostasis and Circadian Rhythmicity: Temperature Regulation; Sleep, Feeding, and Energy Expenditure

    PART IV PHYSICAL SUBSTRATES                                          

    Receptors: Sensory Input; Photic Receptors; Nonphotic Receptors.       

    Pacemakers: The Suprachiasmatic Nucleus; Cellular Processes; Molecular Processes; Other Pacemakers.         

    Afference and Efference

    PART V Applications

    Optimal Timing on Earth and in Space: Best Time for Sports and Intellectual Activities; Space Exploration.

    Jet Lag and Shift Work

    Human Medicine: Chronotherapeutics; Sleep Disorders; Depression.            

    Pet Selection and Veterinary Medicine                                     


     Dictionary of Circadian Physiology: English Dictionary; Language Equivalency; Units of Measurement       
    Organisms Used

    Index

    Editorial Reviews

    “…Refinetti goes to great lengths in defining and explaining many basic concepts with no presumption that undergraduates who would be interested in the subfield of circadian biology would have already covered most of these topics: for example, scientific methods, research ethics, statistics. This probably makes the book easily readable and interesting for some motivated high school students and people with very little science background…This book is seventh heaven for visually oriented learners.”
    —Mehmet Dokucu, PsycCRITIQUES, Vol. 51, No. 43, October 2006
    “Although the size of the book has been expanded three-fold…the popular overall structure of the first edition has been maintained, with five sections covering history and methodology, phemonenology, mechanisms, substrates, and practical applications. Each chapter has extensive tables, figures, photographs…. New features of the second edition include discussions of retinal photoreceptors, non-hypothalamic circadian pacemakers, and genomic and proteomic mechanisms. …the text remains one of the few comprehensive and scientific introductions to circadian physiology that are currently available, and it should remain in popular demand….”
    --Roy J. Shepard, Canadian Journal of Applied Physiology, Vol. 20, Issue 1
    “… reviews rigorously all the basic and applied researches on circadian rhythms published up today. … An included CD-Rom provides a suite of computer programs designed to offer practical experience on a variety of topics. … The rigorous and easy to read way of description of all the aspects of circadian physiology brings clarity to this new science elucidating also the involved mechanisms of action of biological timing. The scheduling of the different topics, the relative use of the CD-Rom included, with 5,000 bibliographic references reported, makes it an easy to read book for Dermatologists, Cosmetic Chemists, Plastic  Surgeons, and of course, all the life scientists interested to better understand the importance of circadian rhythms in the everyday life. The reported selection of facts and theories compiled in an easy way makes the circadian rhythmicity comprehensible to all students and general readers too.”
    — P. Morganti, Editor-in-Chief, in the Journal of Applied Cosmetology, Vol. 25, No. 2, pg. 76-78, April/June 2007
    praise for the first edition
    “Marvelous summary of research on circadian rhythms and the relevance to human behavior.”
    -- James W. Kalat Biological Psychology, 8th Edition
    “Both the book and the programs provide interesting and useful material.”
    -- Stanley Coren, APA Review of Books

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