Table of Contents

MOLECULAR BIOLOGY; Michael Domach
Historical Perspective and Basics of Molecular Biology; Nathan R. Domagalski and Michael Domach
Systems and Technology Involving Bacteria; Nicole Bleckwenn and William Bentley
Recombinant DNA Technology Using Mammalian Cells; Tina Sauerwald and Michael Betenbaugh

TRANSPORT PHENOMENA AND BIOMIMETIC SYSTEMS; Robert J. Fisher
Biomimetic Systems; Robert J. Fisher
Diffusional Processes and Engineering Design; E.N. Lightfoot
Microvascular Heat Transfer; James W. Baish
Perfusion Effects and Hydrodynamics; Robert A. Peattie and Robert J. Fisher
Animal Surrogate Systems; Michael L. Shuler, Sarina G. Harris, and Xinran Li
Arterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease; John M. Tarbell and Yuchen Qui
Control of the Microenvironment; Robert J. Fisher and Robert A. Peattie
Interstitial Transport in the Brain: Principles for Local Drug Delivery; W. Mark Saltzman

BIOTECHNOLOGY; Martin L. Yarmush and Mehmet Toner
Tools for Genome Analysis; Robert Kaiser
Vaccine Production; John G. Aunins, Ann L. Lee, David and B. Volkin
Protein Engineering; Scott Banta
Metabolic Engineering; Scott Banta and Craig Zupke
Monoclonal Antibodies and Their Engineered Fragments; Zaki Megeed, David M. Yarmush, Martin L. Yarmush, and Srikanth Sundaram
Biomolecular Engineering in Oligonucleotide Applications; S. Patrick Walton
Gene Therapy; Cindy Jung and Joseph M. Le Doux
Bio-Nanorobotics: State of the Art and Future Challenges; Ajay Ummat, Gaurav Sharma, C. Mavroidis, and A. Dubey

BIONANOTECHNOLOGY; David E. Reisner
DNA as a Scaffold for Nano-Structure Assembly; Michael Connolly
Directed Evolution of Proteins for Device Applications; Jeremy F. Koscielecki, Jason R. Hillebrecht, and Robert R. Birge
Semiconductor Quantum Dots for Molecular and Cellular Imaging; Andrew Michael Smith and Shuming Nie
Bionanotechnology for Bioanalysis; Lin Wang and Weihong Tan
Nano-Hydroxyapatite for Biomedical Applications; Zongtao Zhang, Yunzhi Yang, and Joo L. Ong
Nanotechnology Provides New Tools for Biomedical Optics; Jennifer L. West, Rebekah A. Drezek, and Naomi J. Halas
Nanomaterials Perspectives and Possibilities in Nanomedicine; Kimberly L. Douglas, Shawn D. Carrigan, and Maryam Tabrizian
Biomedical Nanoengineering for Nanomedicine; Jie Han
Physiogenomics: Integrating Systems Engineering and Nanotechnology for Personalized Medicine; Gualberto Ruaño, Andreas Windemuth, and Theodore R. Holford
Bionanotechnology Patenting: Challenges and Opportunities; Raj Bawa, S.R. Bawa, Stephen B. Maebius, and Chid Iyer

TISSUE ENGINEERING; John P. Fisher and Antonios G. Mikos
Fundamentals of Stem Cell Tissue Engineering; Arnold I. Caplan
Growth Factors and Morphogens: Signals for Tissue Engineering; A. Hari Reddi
Extracellular Matrix: Structure, Function, and Applications to Tissue Engineering; Mary C. Farach-Carson, Roger C. Wagner, and Kristi L. Kiick
Mechanical Forces on Cells; Yan-Ting Shiu
Cell Adhesion; Aaron S. Goldstein
Cell Migration; Gang Cheng and Kyriacos Zygourakis
Inflammatory and Immune Responses to Tissue Engineered Devices; James M. Anderson
Polymeric Scaffolds for Tissue Engineering Applications; Diana M. Yoon and John P. Fisher
Calcium Phosphate Ceramics for Bone Tissue Engineering; P. Quinten Ruhé, Joop G.C. Wolke, Paul H.M. Spauwen, and John A. Jansen
Biomimetic Materials; Andrés J. García
Nanocomposite Scaffolds for Tissue Engineering; Amit S. Mistry, Xinfeng Shi, and Antonios G. Mikos
Roles of Thermodynamic State and Molecular Mobility in Biopreservation; Alptekin Aksan and Mehmet Toner
Drug Delivery; C. Becker and A. Göpferich
Gene Therapy; J.M. Munson and W.T. Godbey
Tissue Engineering Bioreactors; Jose F. Alvarez-Barreto and Vassilios I. Sikavitsas
Animal Models for Evaluation of Tissue-Engineered Orthopedic Implants; Lichun Lu, Esmaiel Jabbari, Michael J. Moore, and Michael J. Yaszemski
The Regulation of Engineered Tissues: Emerging Approaches; Kiki B. Hellman and David Smith
Bioengineering of Human Skin Substitutes; Dorothy M. Supp and Steven T. Boyce
Nerve Regeneration: Tissue Engineering Strategies; Jennifer B. Recknor and Surya K. Mallapragada
Gene Therapy and Tissue Engineering Based on Muscle-Derived Stem Cells: Potential for Musculoskeletal Tissue Regeneration and Repair; Johnny Huard, Baohong Cao, Yong Li, and Hairong Peng
Tissue Engineering Applications - Bone; Ayse B. Celil, Scott Guelcher, Jeffrey O. Hollinger, and Michael Miller
Cartilage Tissue Engineering; Fan Yang and Jennifer H. Elisseeff
Tissue Engineering of the Temporomandibular Joint; Mark E.K. Wong, Kyle D. Allen, and Kyriacos A. Athanasiou
Engineering Smooth Muscle; Yu Ching Yung and David J. Mooney
Esophagus: A Tissue Engineering Challenge; B.D. Ratner, B.L. Beckstead, K.S. Chian, and A.C. Ritchie
Tissue Engineered Vascular Grafts; Rachael H. Schmedlen, Wafa M. Elbjeirami, Andrea S. Gobin, and Jennifer L. West
Cardiac Tissue Engineering: Matching Native Architecture and Function to Develop Safe and Efficient Therapy; Nenad Bursac
Tissue Engineering of Heart Valves; K. Jane Grande-Allen
Tissue Engineering: Use of Stem Cells and Cloning in the Regeneration of Urologic Organs; J. Daniell Rackley and Anthony Atala
Hepatic Tissue Engineering for Adjunct and Temporary Liver Support; François Berthiaume, Arno W. Tilles, Mehmet Toner, Martin L. Yarmush, and Christina Chan
Tissue Engineering of Renal Replacement Therapy; William H. Fissell and H. David Humes
The Bioengineering of Dental Tissues; Rena N. D'Souza and Songtao Shi
Tracheal Tissue Engineering; Brian Dunham, Paul Flint, Sunil Singhal, Catherine Le Visage, and Kam Leong

PROSTHESES AND ARTIFICIAL ORGANS; Pierre M. Galletti and Robert M. Nerem
Artificial Heart and Circulatory Assist Devices; Gerson Rosenberg
Cardiac Valve Prostheses; Gerson Rosenberg
Vascular Grafts; David N. Ku and Robert C. Allen
Artificial Lungs and Blood-Gas Exchange Devices; Pierre M. Galletti and K. Clark
Artificial Kidney; C. Mavroidis
Peritoneal Dialysis Equipment; Michael J. Lysaght and John Moran
Therapeutic Apheresis and Blood Fractionation; Andrew L. Zydney
Liver Support Systems; Pierre M. Galletti and Hugo O. Jauregui
Artificial Pancreas; Pierre M. Galletti, Clark K. Colton, Michel Jaffrin, and Genard Reach
Nerve Guidance Channels; Robert F. Valentini
Tracheal, Laryngeal, and Esophageal Replacement Devices; Tatsuo Nakamura and Yasuhiko Shimizu
Artificial Blood; Marcos Intaglietta and Robert M. Winslow
Artificial Skin and Dermal Equivalents; Ioaniss V. Yannas

ETHICS; David E. Reisner
Beneficence, Nonmaleficence, and Medical Technology; Joseph D. Bronzino
Ethical Issues Related to Clinical Research; Joseph D. Bronzino
INDEX