Biologically Active Natural Products: Pharmaceuticals

Published:
July 27, 1999 by CRC Press - 296 Pages
Editor(s):
Stephen J. Cutler, Mercer University, Atlanta, Georgia, USA; Horace G. Cutler, Mercer University, Atlanta, Georgia, USA

Purchasing Options

Hardback
$199.95
Add to cart
ISBN 9780849318870
Cat# 1887
 

Features

  • Discusses fractionation of plants to discover substances that combat cancer
  • Presents structure-activity relationships of antimalarials
  • Includes plant-derived products and their analogs, with antitumor, anti-HIV, and antifungal activity

    • Summary

    Biologically Active Natural Products: Pharmaceuticals demonstrates the connections between agrochemicals and pharmaceuticals and explores the use of plants and plant products in the formulation and development of pharmaceuticals. Experts from around the world examine a multitude of topics, including evaluation of extracts from tropical plants for potential anticancer activity and cancer chemopreventive activity; use of Chinese lacquer tree sap products as pharmaceutical intermediates; and new approaches to drug discovery from the rainforest.

    Table of Contents

    CONNECTIONS BETWEEN AGROCHEMICALS AND PHARMACEUTICALS
    -David E. Wedge and N. Dwight Camper
    FRACTIONATION OF PLANTS TO DISCOVER SUBSTANCES TO COMBAT CANCER
    -A.D. Kinghorn, et. al.
    THERAPETUIC POTENTIAL OF PLANT-DERIVED COMPOUNDS: REALIZING THE POTENTIAL
    -J.S. Miller and R.E. Gereau
    BIODIVERSITY CONSERVATION, ECONOMIC DEVELOPMENT, AND DRUG DISCOVERY IN SURINAME
    -D.G.I. Kingston, et. al.
    RECENT TRENDS IN THE USE OF NATURAL PRODUCTS AND THEIR DERIVATIVES AS POTENTIAL PHARMACEUTICAL AGENTS
    -G. Majetich
    HIGHLIGHTS OF RESEARCH ON PLANT-DERIVED NATURAL PRODUCTS AND THEIR ANALOGS WITH ANTITUMOR, ANTI-HIV, AND ANTIFUNGAL ACTIVITY
    -K-H. Lee
    DISCOVERY OF ANTIFUNGAL AGENTS FROM NATURAL SOURCES: VIRULENCE FACTOR TARGETS
    -A.M. Clark and L.A. Walker
    REACTIVE QUINONES: FROM CHEMICAL DEFENSE MECHANISMS IN PLANTS TO DRUG DESIGN
    -R.A. Hudson and L.V.M. Tillekeratne
    STRUCTURE-ACTIVITY RELATIONSHIPS OF PEROXIDE BASED ARTEMISININ ANTIMALARIALS
    -M.A. Avery, G. McLean, G. Edwards, and A. Ager
    NATURALLY OCCURRING ANTIMUTAGENIC AND CYTOPROTECTIVE AGENTS
    -L.A. Mitscher S.P. Pillai, S.R. Menon, C.A. Pillai, and D.M. Shankel
    LOBELINE: A NATURAL PRODUCT WITH HIGH AFFINITY FOR NEURONAL NICOTINIC RECEPTORS AND A VAST POTENTIAL FOR USE IN NEUROLOGICAL DISORDERS
    -C.R. McCurdy, R.L. Miler, and J.W. Beach
    PROTEIN KINASE C INHIBITORY PHENYLPROPANOID GLYCOSIDES FROM POLYGONUM SPECIES
    -A.T. Sneden
    THWARTING RESISTANCE: ANNONACEOUS ACETOGENINS AS NEW PESTICIDAL AND ANTITUMOR AGENTS
    -H.A. Johnson, N.H. Oberlies, F.Q. Alali, and J.L. McLaughlin
    A STRATEGY FOR RAPID IDENTIFICATION OF NOVEL THERAPEUTIC LEADS FROM NATURAL PRODUCTS
    -K. A. Alvi
    DYNAMIC DOCKING STUDY OF THE BINDING OF 1-CHLORO-2, 4-DINITROBENZENE IN THE PUTATIVE ELECTROPHILE BINDING SITE OF NATURALLY OCCURRING HUMAN GLUTATHIONE S-TRANSFERASE PI ALLELO-POLYMORPHIC PROTEINS
    -J.K. Buolamwini and F. Ali-Osman
    PANAX GINSENG: STANDARDIZATION AND BIOLOGICAL ACTIVITY
    -F. Soldati
    MARINE NATURAL PRODUCTS AS LEADS TO DEVELOP NEW DRUGS AND INSECTICIDES
    -K.A. ElSayed, D.C. Dunbar, P. Bartzel, J.K. Zjawiony, W. Day, and M.T. Hamann
    COMMERCIALIZATION OF PLANT-DERIVED NATURAL PRODUCTS AS PHARMACEUTICALS: A VIEW FROM THE TRENCHES
    -J.D. McChesney

    Editorial Reviews

    "…its chapters are well referenced…index covers the compounds presented in each chapter…Pharmacy schools that have active natural products programs should purchase this book for its library…faculty, post-doctral fellows and senior graduate students should consider it for personal purchase."
    --American Journal of Pharmaceutical Education, Vol. 64

    Related Titles