The brain in the second trimester, the subject of Volume
3, is nearing anatomical maturity throughout the brainstem. In contrast, the neurogenesis and neuronal migration are still in progress in the cerebral cortex and cerebellum. Consequently, the authors chose to focus on the migration, sojourning, and settling of the neuronal populations belonging to these immature structures.
These observations can help researchers develop a better understanding of normal brain development at this formative stage. In this volume, the authors offer consideration of a new concept regarding human cortical development: the identification of the stratified transitional field (STF), which continues to play an important role in later stages. Until recently regarded as simply an intermediate and transitional layer of little significance, modern imaging techniques have shown that it is in the STF where cortical neural connections are first specified. Among other salient points, the development of this field may well bring to light those disruptions during development that lead to cerebral palsy.
INTRODUCTION
Organization of the Atlas
Specimens
Photography and Computer Processing
Identification of Brain Structures
Major Developmental Brain Structures in the Second Trimester
The Cortical Stratified Transitional Field
References
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This book "…should greatly advance our understanding of prenatal development of the brain, making immeasurable contributions to education, research and training of medical specialists and other personnel."
Worldtrade.com
"The atlas, however, is impressive and an excellent exposition of the fetal human brain development which contains valuable information not readily accessible elsewhere... will be a worthwhile addition to the libraries of neurosciences whose pursuits require ready access to an authoritative atlas on development of the human brain in the second trimester. This user-friendly atlas will also be useful to residents, and even graduate students needing to learn about the human brain development." - Hajnalka Abraham, Journal of Chemical Neuroanatomy, Feb. 2009, Vol. 36