Offers the first complete treatment of design automation for reconfiguarable microfluidic systemsPresents methodologies and tools for top-down MEF system designs that reduce design time and costs while allowing high-volume productionUses an integrated design environment based on SystemCIncludes case studies that illustrate the techniques in real-world applicationsProvides a performance comparison between continuous-flow and droplet-based MEF systems
Composite systems that integrate microelectromechanical and microelectrofluidic (MEF) components with electronics are emerging as the next generation of system-on-a-chip (SOC) designs. However, there remains a pressing need for a structured methodology for MEFS design automation, including modeling techniques and simulation and optimization tools.
Integrating top-down and bottom-up design philosophies, Microelectrofluidic Systems presents the first comprehensive design strategy for MEFS. This strategy supports hierarchical modeling and simulation from the component level to the system level. It leads to multi-objective optimization tools valuable in all phases of the design process, from conceptualization to final manufacturing. The authors begin by defining the basic variables and elements needed to describe MEFS behavior, then model that behavior across three layers of abstraction: the low-level component, high-level reconfigurable architecture, and bio/chemical application layers. They have developed a hierarchical integrated design environment with SystemC and present its architecture and associated functional packages.
Microelectrofluidic Systems is visionary in its leverage of electronic design principles for microsystem design and heralds a new era of automated SOC design. The strategy it presents holds the potential for significant reductions in design time and life-cycle maintenance costs, and its techniques and tools for robust design and application flexibility can lead to the high-volume production needed for the inevitably growing product market.
Table of Contents
Modeling and Simulation Issues
Modeling and Simulation Needs
MEFS Dynamic Modeling and Simulation at Circuit Level
MEFS System-Level Modeling and Simulation
SYSTEMC-BASED HIERARCHICAL DESIGN ENVIRONMENT
Suitability of Modeling Languages for Hierarchical Design
Building Design Environment with SystemC
SYSTEM-LEVEL SIMULATION AND PERFORMANCE EVALUATION
MEFS Computing and Architecture
Hierarchical Modeling and Simulation Methodology
Micro-Chemical Handling System
System Performance Analysis and Design Optimization
Simulation Design Methodology
On-Target Design Optimization
Robust Design Optimization
Application Flexibility Optimization
Continuous-Flow PCR System
Droplet-Based PCR System
Comparison Between Continuous-Flow PCR and Droplet PCR
Scheduling of Microfluidic Operations for Reconfigurable Two-Dimensional Electrowetting Arrays
VHDL Queuing Model
Hierarchical Environment with SystemC
Keywords: Nanoscience, Nanotechnology
"[In this textbook] microelectrofluidic systems are thoroughly explained and defined in an understandable manner (which at times is challenging in an engineering text). … highly informative in its descriptive premise of top-down modeling and simulation…This text opens up a number of directions for research into top-down design for microelectrofluidic systems. … The information contained in the book will help achieve reduced costs and design stability for microelectrofluidic systems in an automated design market."
- IEEE Engineering in Medicine and Biology