Microelectrofluidic Systems

Microelectrofluidic Systems: Modeling and Simulation

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Features

  • Offers the first complete treatment of design automation for reconfiguarable microfluidic systems
  • Presents methodologies and tools for top-down MEF system designs that reduce design time and costs while allowing high-volume production
  • Uses an integrated design environment based on SystemC
  • Includes case studies that illustrate the techniques in real-world applications
  • Provides a performance comparison between continuous-flow and droplet-based MEF systems
  • Summary

    Composite systems that integrate microelectromechanical and microelectrofluidic (MEF) components with electronics are emerging as the next generation of system-on-a-chip (SOC) designs. However, there remains a pressing need for a structured methodology for MEFS design automation, including modeling techniques and simulation and optimization tools.

    Integrating top-down and bottom-up design philosophies, Microelectrofluidic Systems presents the first comprehensive design strategy for MEFS. This strategy supports hierarchical modeling and simulation from the component level to the system level. It leads to multi-objective optimization tools valuable in all phases of the design process, from conceptualization to final manufacturing. The authors begin by defining the basic variables and elements needed to describe MEFS behavior, then model that behavior across three layers of abstraction: the low-level component, high-level reconfigurable architecture, and bio/chemical application layers. They have developed a hierarchical integrated design environment with SystemC and present its architecture and associated functional packages.

    Microelectrofluidic Systems is visionary in its leverage of electronic design principles for microsystem design and heralds a new era of automated SOC design. The strategy it presents holds the potential for significant reductions in design time and life-cycle maintenance costs, and its techniques and tools for robust design and application flexibility can lead to the high-volume production needed for the inevitably growing product market.

    Table of Contents

    INTRODUCTION
    Modeling and Simulation Issues
    Modeling and Simulation Needs
    Overview
    HIERARCHICAL MODELING
    MEFS Dynamic Modeling and Simulation at Circuit Level
    MEFS System-Level Modeling and Simulation
    Conclusion
    SYSTEMC-BASED HIERARCHICAL DESIGN ENVIRONMENT
    Suitability of Modeling Languages for Hierarchical Design
    Building Design Environment with SystemC
    Conclusion
    SYSTEM-LEVEL SIMULATION AND PERFORMANCE EVALUATION
    MEFS Computing and Architecture
    Hierarchical Modeling and Simulation Methodology
    Micro-Chemical Handling System
    System Performance Analysis and Design Optimization
    Conclusion
    CIRCUIT-LEVEL OPTIMIZATION
    Simulation Design Methodology
    Optimization Verification
    On-Target Design Optimization
    Robust Design Optimization
    Application Flexibility Optimization
    Conclusion
    PERFORMANCE EVALUATION
    Introduction
    Continuous-Flow PCR System
    Droplet-Based PCR System
    Comparison Between Continuous-Flow PCR and Droplet PCR
    Scheduling of Microfluidic Operations for Reconfigurable Two-Dimensional Electrowetting Arrays
    CONCLUSION
    APPENDICES
    VHDL Queuing Model
    Hierarchical Environment with SystemC

    Keywords: Nanoscience, Nanotechnology

    Editorial Reviews

    "[In this textbook] microelectrofluidic systems are thoroughly explained and defined in an understandable manner (which at times is challenging in an engineering text). … highly informative in its descriptive premise of top-down modeling and simulation…This text opens up a number of directions for research into top-down design for microelectrofluidic systems. … The information contained in the book will help achieve reduced costs and design stability for microelectrofluidic systems in an automated design market."
    - IEEE Engineering in Medicine and Biology

     
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