Handbook of Laboratory Animal Science, Second Edition: Essential Principles and Practices, Volume I

Published:
October 28, 2002 by CRC Press - 566 Pages
Editor(s):
Jann Hau, University of Copenhagen & Rigshospitalet, Denmark; Steven J. Schapiro, The University of Texas MD Anderson Cancer Center, Bastrop, USA; Jann Hau, University of Copenhagen & Rigshospitalet, Denmark

Purchasing Options

Hardback
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ISBN 9780849310867
Cat# 1086
 

Features

  • Detailed descriptions of laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments
  • Discussion of general methods including experimental design and statistical evaluations, non-surgical and surgical techniques, anesthesia, and post-mortem examinations
  • Thoroughly revised chapters on occupational health, techniques and procedures in genetic engineering, and experimental design and statistics
  • Expanded coverage of safety and security in laboratory animal facilities, humane endpoints and the treatment of pain in lab animals, surgical techniques, minimal access techniques, Australasian legislation and regulation of the use of lab animals, and the use of the Web as a resource
  • New, streamlined chapter combines the review of alternative techniques to animal experimentation with the use of isolated organs, cell cultures, and computer simulations

    • Summary

    The second edition of an international bestseller, this book provides veterinary specialists as well as veterinary and biomedical researchers with detailed information about laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments. Completely revised and updated, Volume I now contains expanded coverage of topics such as procedures in genetic engineering, surgical techniques, and humane endpoints and the treatment of pain and suffering in laboratory animals. It includes a new, streamlined chapter that combines the review of alternative techniques to animal experimentation such as the use of isolated organs, cell cultures, and computer simulations.

    Table of Contents

    The Contribution of Laboratory Animals to Medical Process, F. Grieder and J. Strandberg
    Animal Research Ethics, A. Olsson, P. Robinson, K. Pritchett, and P. Sandøe
    An Overview of Global Legislation, Regulation and Policies on the Use of Animals for Scientific Research, Testing or Education, K. Bayne and P. de Greeve
    Assessment of Animal Care and Use Programs and Facilities, J. Miller, H. van Herck, R.L. Larson
    Education and Training, N. Duffee, T. Nevalainen and J. Hau
    Laboratory Animal Science and Service Organizations, P. Vergara and G. Demers
    Laboratory Animal Allergy, R. Preece and A. Renström
    Equipment for Conventional, Barrier, and Containment Housing Systems, J. Hessler and U. Höglund
    Laboratory Animal Genetics and Genetic Quality Control, M. Festing
    Phenotypic Characterization of Genetically Engineered Mice
    C. Rubin, S. Knoblaugh, W. Ladiges
    Health Status and Health Monitoring, A. Kornerup Hansen
    Nutrient Requirements, Experimental Design and Feeding Schedules in Animal Experimentation, J. Ritskes-Hoitinga and A. Chwalibog
    Impact of the Biotic and Abiotic Environment on Animal Experiments, N. Johnston and T. Nevalainen
    Experimental Design and Statistical Analysis, M. Festing and B. Weigler
    Common Nonsurgical Techniques and Procedures, C. Pekow and V. Baumans
    Production of Polyclonal and Monoclonal Antibodies, C. Hendriksen and J. Hau
    Laboratory Animal Analgesia, Anesthesia and Euthanasia, P. Hedenqvist and L. Hellebrekers
    Welfare Assessment and Humane Endpoints, D. Morton and J. Hau
    Surgery: Basic Principles and Procedures, H. Waynforth, M. Swindle, H. Elliott and A. Smith
    Microsurgical Procedures in Experimental Research, S. Steinbrüchel
    Postmortem Procedures, R. Feinstein and K. Waggie
    Alternatives: Refinement, Reduction and Replacement of Animal Use in the Life Sciences, A. Goldberg and K. Drnec

    Editorial Reviews

    "[A] valuable reference book, and potentially a course book for undergraduate and graduate laboratory animal science courses. … [T]he text is well organized and well referenced. I would highly recommend this book as a reference text for all scientists using traditional laboratory animal species … ."
    - Contemporary Topics in Laboratory Animal Science, Vol. 43, No. 5, Sept. 2004


    "…well written, user friendly…it fills a current void by collecting together current practices in the scientific use of animals. Each chapter is well referenced and the book would be a valuable addition to the reference collections of animal facilities and research establishments."
    - in Animal Welfare

    "Hau and Van Hoosier have drawn together information of the highest quality. . . both volumes of this book will be valuable additions to the shelves of any veterinary surgeon involved in the field, either as a named vet or as a member of the multidisciplinary scientific team required in modern biomedical research."
    - in The Veterinary Record

    "The text is quite easy to navigate using the chapter contents and index. The photographs and tables are clear and well used throughout. …The vast scope of information that this handbook contains is diverse, informative, and quite useful. The strength of these volumes is in their ability to cover a broad range of topics yet in such detail. This set would be an asset to the graduate student and researcher needing an excellent reference manual."
    - in Animal Lab News

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