Table of Contents

"Introduction References Rates, Rate Constants, and Order Order Rates and Rate Constants Active and Passive Transport Introduction Passive Transport Active Transport References Pharmacokinetics Introduction Drug Disposition Constant-Rate Intravenous Infusion Compartmental Models and Their Limitations Absorption Rate Constants References Biopharmaceutics Extravascular Administration Absorption of Drugs from the Gastrointestinal Tract Factors Influencing Bioavailability Evaluation of the Bioavailability of a Single Drug Drug Delivery to Prolong Duration References Dosage Regimens Introduction Accumulation During Repetitive Dosing Adjustment of Dosage Regimen in Renal Failure Multiple Dosing of Constant-Rate Intravenous Infusions References Pharmacokinetic Aspects of Structural Modifications in Drug Design and Therapy Introduction Antimicrobial Agents Pharmacokinetics of Prodrugs Stereoisomers References Pharmacokinetic Applications in Clinical Practice Introduction Pharmacokinetic Drug Interactions Clinical Pharmacokinetics "