Metal Ions in Biological Systems

Metal Ions in Biological Systems: Volume 42: Metal Complexes in Tumor Diagnosis and as Anticancer Agents

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Summary

Offering an authoritative and timely account by twenty-nine internationally recognized experts, Metal Ions in Biological Systems: Metal Complexes in Tumor Diagnosis and as Anticancer Agents is devoted solely to the vital research area concerning metal complexes in cancer diagnosis and therapy. In fourteen stimulating chapters, the book focuses on diagnostic tools such as magnetic resonance imaging (MRI), luminescent probes, and radiopharmaceuticals, including radiometallo-labeled peptides and assesses the role of metal ions, especially iron, in the action of antibiotics employed in anticancer chemotherapy.

Table of Contents

Magnetic Resonance Contrast Agents for Medical and Molecular Imaging, M.J. Allen and T.J. Meade
Luminescent Lanthanide Probes as Diagnostic and Therapeutic Tools, J.-C. Bünzli
Radio-Lanthanides in Nuclear Medicine, F. Rösch and E. Forssell-Aronson
RadioMetallo-Labeled Peptides in Tumor Diagnosis and Therapy, M. Ginj and H.R. Maecke
Cisplatin and Related Anticancer Drugs. Recent Advances and Insights, K.R. Barnes and S.J. Lippard
The Effect of Cytoprotective Agents in Platinum Anticancer Therapy, M.A. Jakupec, M. Galanski, and B.K. Keppler
Antitumor Activity of Trans-Platinum Species, G. Natile and M. Coluccia
Polynuclear Platinum Drugs, N.P. Farrell
Platinum(IV) Anticancer Complexes, M.D. Hall, R. Dolman, and T.W. Hambley
Ruthenium Anticancer Drugs, E. Alessio, G. Mestroni, A. Bergamo, and G. Sava
Antitumor Titanium Compounds and Related Metallocenes, F. Caruso and M. Rossi
Gold Complexes as Antitumor Agents, L. Messori and G. Marcon
Gallium and Other Main Group Metal Compounds as Antitumor Agents, M.A. Jakupec
Metal Ion Dependent Antibiotics in Chemotherapy, D.H. Petering, C. Xia, and W.E. Antholine

Editorial Reviews

"This is one of two recent volumes in a most successful series publishes since 1973 and which enjoys world renown and respect as both reference and as training material; the current volume is no exception. … [T]his is a gem of a book for both newcomers and established researchers in the field; long may they continue!"
- Applied Organometallic Chemistry, 2005


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