Oxidative Stress, Inflammation, and Health

Series:
Oxidative Stress and Disease
Published:
May 24, 2005 by CRC Press - 660 Pages
Editor(s):
Young-Joon Surh, Seoul National University, South Korea

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Hardback
$219.95
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ISBN 9780824727338
Cat# DK2987
 

Features

Edited by world-renowned authorities on the subject, this guide

  • provides a mechanistic basis for cellular alterations by pro-oxidative and pro-inflammatory insults
  • introduces the most recent methods to combat oxidative stress and inflammatory cell/tissue damage
  • contains the latest studies on the regulation of gene expression by oxidants and antioxidants
  • studies chemopreventive strategies targeting intracellular signaling
  • examines the use of natural antioxidants for disease prevention

    • Summary

    Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-analyzing the implications of oxidative stress and inflammatory damage in the pathogenesis of human disorders such as cancer, neurodegenerative disease, and diabetes.

    Table of Contents

    Oxidants and Antioxidants: Mechanism of Action and Regulation of Gene Expression by Bio?avonoids
    Transcriptional Regulation of Cellular Antioxidant Defense Mechanisms
    Redox Regulation of In?ammatory Tissue Damage by Thioredoxin
    Regulation of NF-kB-Driven In?ammatory Genes by Phytoestrogens
    Nuclear Factor-kB as Target for Chemoprevention
    Heme Oxygenase-1: An Emerging Major Cellular Defense Against Cigarette Smoke-Induced Oxidative Stress and Cytotoxicity
    Biphasic Induction of HO-1 in Macrophages Treated with Lipopolysaccharide: Role of HO-1 Induction in Cell Survival from Oxidative Stress
    The Role of Ga12 Proteins in the PKC and JNK-Dependent Induction of NOS by Thrombin
    Actions of 8-Hydroxyguanine in DNA
    Role of Oxidative Stress in Hypercholesterolemia-Induced In?ammation
    Oxidative Stress in Rheumatoid Arthritis
    Roles of Carbon Monoxide and Nitric Oxide in Liver Damage
    Role of Oxidative Stress and In?ammatory Response in Smokers and Chronic Obstructive Pulmonary Disease
    Association of Chronic In?ammation with Carcinogenesis: Implications of Anti-In?ammatory Strategies for Cancer Prevention
    Molecular In?ammation as an Underlying Mechanism of Aging: The Anti-in?ammatory Action of Calorie Restriction
    Oxidative Stress in Mitochondria: The Involvement in Neurodegenerative Diseases
    Implications of In?ammatory Stress in Alzheimer's Disease
    Biomarkers for Evaluating Antioxidant Effects
    Antioxidant and Neuroprotective Potentials
    Resveratrol-A Unique Polyphenolic Antioxidant Present in Grape Skins and Red Wine-Is a Preventive Medicine Against a Variety of Degenerative Diseases
    Molecular Mechanisms of Prevention Against Allergic Rhinitis by Aller-7, A Novel Polyherbal Formulation
    Antioxidant Character of Selenium and Its Survival Signals by Activation of PI3-K/Akt Pathways
    Neuroprotection by Rasagiline and Related Propargylamines Is Mediated by Suppression of Mitochondrial Death Signal and Induction of Antiapoptotic Genes
    Index

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