Applied Electrospray Mass Spectrometry: Practical Spectroscopy Series Volume 32

Series:
Practical Spectroscopy
Published:
February 28, 2002 by CRC Press - 446 Pages
Editor(s):
Birendra N. Pramanik, Schering-Plough Research Institute, Kenilworth, New Jersey; A.K. Ganguly, Stevens Institute of Technology, Hoboken, New Jersey, USA; Michael L. Gross, Washington University, Saint Louis, Missouri, USA

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Hardback
$259.95
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ISBN 9780824706180
Cat# DK1852
 

Features

  • Detailed advances in proteomics, noncovalent complexes of ligands and proteins, nanoflow methods, and combinatorial chemistry
  • Discusses strategies to determine the structure and mechanisms of numerous compound classes, including synthetic organic compounds, B-lactams, steroids, macrocyclic compounds, peptides, glycoproteins, oligosaccharides, proteins, lipids, and polymers
  • Covers sensitive ionization methods for large biomolecules and the profiling of metabolites in in vivo and in vitro matrices

    • Summary

    Discussing strategies to determine the structure and machanisms of numerous compound classics, this book covers new chemical and elctrophoretic techniques for rapid sample preconcentration and separation. It summarizes breakthroughs in the theory and instrumentation of electrospray mass spectrometry in pharmaceutical and biomedical applications, provides practical examples for the characterization of peptides, proteins, and glycoproteins, includes applications in proteomics, combinatorial chemistry, and drug characterization. Topics include chemical and electrophoretic techniques for rapid sample preconcentration and separation, screening processes for proteins from libraries of compounds, protein folding and dynamics, and more.

    Editorial Reviews

    "…summarizes the most recent breakthroughs in the theory and instrumentation of electrospray mass spectrometry."
    -International Journal of Environmental Analytical Chemistry

    "…excellent."
    -Journal of the American Chemical Society

    "…a full and clear discussion…"…covers a broad range of the modern applications of ESI-MS….well-written and structured."
    -Journal of Analytical Atomic Spectrometry

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