Peptide Antibiotics: Discovery Modes Of Action And Applications
Summary
This reference summarizes the latest research on the structure, function, and design of synthetic and natural peptide antibiotics, describing practical applications of these compounds in food preservation and packaging, and in the prevention and treatment of infectious diseases by direct anti-bacterial action and as part of the adaptive immune response.
Peptide Antibiotics discusses these unique compounds and their many and exciting applications, including:
With contributions from 19 world-renowned experts in the field, Peptide Antibiotics is an indispensable source of information for pharmaceutical scientists, medicinal and organic chemists and biochemists, microbiologists, infectious disease specialists, molecular biologists, and upper-level undergraduate and graduate students in these disciplines.
Table of Contents
Introduction to the Peptide Antibiotics
Harry W. Taber
Sources of Antimicrobial Peptides
Chemistry and Applications of Synthetic Antimicrobial Peptides
David Andreu and Luis Rivas
Lanthionine-Containing Bacterial Peptides
Ulrike Pag and Hans-Georg Sahl
Unmodified Peptide-Bacteriocins (Class II) Produced by Lactic Acid Bacteria
Ingolf F. Nes, Helge Holo, Gunnar Fimland, Håvard Hildeng Hauge, and Jon Nissen-Meyer
Insect Cationic Antimicrobial Peptides
Charles Hetru, Jules A. Hoffmann, and Robert E. W. Hancock
Mammalian Antimicrobial Peptides
Charles L. Bevins and Gill Diamond
Potential Applications of Peptides
Exploitation of Lantibiotic Peptides for Food and Medical Uses
Máire P. Ryan, Colin Hill, and R. Paul Ross
Amphibian Antimicrobial Peptides
Michael A. Zasloff
Index
