This source presents the principles of cell biology, cellular pathways, and their implications for drug development in oncology. Using state-of-the-art and evidence-based literature references and reviews, with illustrations as necessary, the authors present an overview that is both reliable and easily understood.
Principles of Normal Cell Biology. Principles of Normal Immunology. Principles of Tumor Biology. Basic Tumor Immunology. Limitless Replicative Potential. Self-Sufficiency in Growth Signals. Insensitivity to Anti-Growth Signals. Evading Apoptosis. Angiogenesis. Tissue Invasion and Metastasis. Treatment. Treatment Evaluation
"This book is featured in 18 short, and at the same time exhaustive, chapters whose aim, true to Jose Baselga's foreword, is to facilitate the understanding of the key areas of translational research. […] I am deeply convinced this handbook provides a rewarding and enjoyable reading, embodying a common, useful tool of discussion between the research and the clinical word." Marco A. Pierotti, ESMO NewsletterOctober-December 2007